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Diss Factsheets
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EC number: 288-509-6 | CAS number: 85736-97-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1989-07-18 to 1989-07-20
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Principles of method if other than guideline:
- Five concentrations of the test material (1, 10, 100, 1000, 10000 mg/l) were tested. As the solubility of the substance was far exceeded and no
physical inhibitory effects (e.g. agglomeration of activated sludge) were observed, no further tests were performed. - GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- - Sample storage conditions before analysis: 20 °C ±2 °C
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
- Details on inoculum:
- - Pretreatment:
A sample of mixed liquor from the sewage plant was obtained and aerated during transportation to the laboratory.
Two samples of 10 ml were weighed and dried at 105 °C. The amount of solids was calculated and the wet sludge suspended with isotonic solution to yield a concentration of 3 g suspended solids per litre. Subsequently, the activated sludge was amended with 50 ml synthetic sewage per litre and aerated at 20 °C ±2 °C overnight.
Before use the amount of solids was determined and adjusted to 3 g / l. Aditionally, the pH-value was controlled. An adjustment was not necessary as the pH was in the accepted range of 6.0 – 8.0 - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 180 min
- Test temperature:
- 20 °C ±2 °C
- pH:
- pH 6 - 8
- Nominal and measured concentrations:
- 1, 10, 100, 1000 and 10000 mg/l
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol
- Duration:
- 180 min
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Details on results:
- Five concentrations of the test material (1, 10, 100, 1000, 10000 mg/l) were tested. As the solubility of the substance was far exceeded and no
physical inhibitory effects (e.g. agglomeration of activated sludge) were observed, no further tests were performed. - Results with reference substance (positive control):
- - Relevant effect levels:
The EC50 (3 hours) of 3,5-dichlorophenol was in the accepted range of 5 to 30 mg/l.
In every test the two control respiration rates were within 15 % of each other - Validity criteria fulfilled:
- yes
- Conclusions:
- Isotridecyl methacrylate is of low toxicity to microorganisms relevant for biodegradation.
The EC50 (3 h) for the inhibition of biodegradation was > 10000 mg/L. - Executive summary:
Isotridecyl methacrylate was tested for toxicity to bacteria relevant for the biodegradation of the substance. In concentrations up to 10000 mg/l, which are far exceeding the water solubility of the substance, no inhibition of the oxygen consumption of the bacteria was observed within 180 min.
Therefore, it can be concluded that isotridecyl methacrylate is non-toxic to bacteria.
NOTE: Any of data in this dataset are disseminated by the European Union on a right-to-know basis and this is not a publication in the same sense as a book or an article in a journal. The right of ownership in any part of this information is reserved by the data owner(s). The use of this information for any other, e.g. commercial purpose is strictly reserved to the data owners and those persons or legal entities having paid the respective access fee for the intended purpose.
Reference
Description of key information
3 h EC50 > 10000 mg/L (equivalent to OECD TG 209, RL1, GLP)
Key value for chemical safety assessment
- EC50 for microorganisms:
- 10 000 mg/L
Additional information
Isotridecyl methacrylate was tested for toxicity to bacteria relevant for the biodegradation of the substance. In concentrations up to 10000 mg/l, which are far exceeding the water solubility of the substance, no inhibition of the oxygen consumption of the bacteria was observed within 180 min.
Therefore, it can be concluded that Isotridecyl methacrylate is non-toxic to bacteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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