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EC number: 310-202-3 | CAS number: 37206-42-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- 1,1''-isopropylidenebis(ethylferrocene)
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- 1,1''-isopropylidenebis(ethylferrocene)
- PBT status:
- the substance is not PBT / vPvB
- Justification:
P/vP 1,1'-Bis(ferrocenyl)octane, CAS Number 501410 -94 -2, EC Number 479 -710 -1
The ready biodegradability of 1,1'-Bis(ferrocenyl)octane, CAS Number 501410-94-2, EC Number 479-710-1 was investigated in accordance with the standardised guideline OECD 301D. 1,1'-Bis(ferrocenyl)octane, CAS Number 501410-94-2, EC Number 479-710-1 is not readily biodegradable. In the 28 day OECD 301D study the substance demonstrated 3% biodegradation.
P/vP Ferrocene, CAS Number 102 -54 -5, EC Number 203 -039 -3
The ready biodegradability of iron(2+) dicyclopenta-2,4-dienide (Ferrocene), CAS Number 102-54-5, EC Number 203-039-3 was investigated in accordance with the standardised guideline OECD 301B. In this study ferrocene failed to meet the criteria for ready biodegradability. However, it is regarded as Inherently biodegradable since by day 27 degradation was 56%, rising to 73% by day 41. Degradation occurs in a linear pattern so, by extrapolation, 100% mineralisation will occur.
Therefore, inherent biodegradation of 1,1"-isopropylidenebis(ethylferrocene), CAS Number 37206 -42 -1, EC Number 310 -202 -3, is to be anticipated.
B/vB
The log octanol-water (Log Koc) partition coefficient of the substance 1,1"-isopropylidenebis(ethylferrocene), CAS Number 37206-42-1, EC Number 310-202-3 was investigated using KOWWIN v 1.68, (EPI Suite version 4.11).
The log octanol-water (Log Koc) partition coefficient of the substance 1,1"-isopropylidenebis(ethylferrocene), CAS Number 37206-42-1, EC Number 310-202-3 was estimated to be 9.25.
Furthermore, the bioconcentration factor was estimated to be 1.05 E+003 using BCFBAF (v3.01), EPI suite (v4.11).
The read across substance, 1,1-bis-(ferrocenyl)octane is potentially a B based on the Log Pow of 4.6 +/- 0.18 in a study performed to OECD guideline 107.
The read-across substance Ferrocene is regarded as not B / vB based on Log Kow <= 4.5: In a Study performed to OECD Guideline 107, ferrocene had a log Pow of 3.711 at 22°C.
T
1) In a Study performed on ferrocene to OECD Guideline 211, NOEC of <0.01 mg/l was reported.
2) In a study performed on ferrocene to OECD Guideline 422, ferrocene was found to have reproductive and developmental effects and is classified as a Reproductive toxicant category 2
3) In repeated dose studies (oral and dermal) performed on ferrocene, ferrocene was found to have repeated dose effects and is classified as STOT RE 2 (oral and inhalation) and R48/20/22.
Conclusion on T properties: T
By implication 1,1"-isopropylidenebis(ethylferrocene), CAS Number 37206 -42 -1, EC Number 310 -202 -3 may therefore be regarded as a T.
1,1'-bis-(ferrocenyl)octane is not regarded as T since :-
LC50 (fish), OECD 203, > 0.45 mg/L
EC50 (Daphnia), > 0.36 mg/L
EC40 (algae), OECD 201, > 0.36 mg/L
Reference
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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