Reaction mass of 1,2,3,4,4a,5,6,7-octahydro-2,5,5-trimethyl-2-naphthol and 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butan-2-one and 4-(2,6,6-trimethyl-2-cyclohexen-1-yl)butan-2-one

Adsorption / desorption

Link to relevant study record(s)

Reference

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

key study

Study period:

May 17, 2021 - June 1, 2021

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

HPLC estimation method

Media:

soil/sewage sludge

Specific details on test material used for the study:

Substance name POLYAMBROL
Chemical name Reaction mass of 1,2,3,4,4a,5,6,7-octahydro-2,5,5-trimethyl-2-naphthol and 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butan-2-one and 4-(2,6,6-trimethyl-2-cyclohexen-1-yl)butan-2-one
Description Colourless to pale yellow liquid
Test substance storage Keep container tightly closed in a cool, well-ventilated place. Store in a dry place. Protect from direct sunlight. Remove all sources of ignition. Keep away from sources of heat (e.g. hot surfaces), sparks and open flames.

Radiolabelling:

no

Test temperature:

between 29.8°C and 30.1°C

Details on study design: HPLC method:

A stock solution of the test item was be prepared at a concentration of 1 g/L in acetone. A diluted solution was prepared in the HPLC mobile phase. Sodium nitrate was added to this solution. These concentrations were adjusted depending on the response intensity of the compound on the system.
The dead time t0 was measured by using a non-retained compound (sodium nitrate) which was present in the reference items mix and in the test item solution.

Key result

Sample No.:

#1

Type:

log Koc

Value:

> 2.25 - < 3.18 dimensionless

pH:

5

Temp.:

30 °C

Matrix:

Soil and Sewage Sludge

Details on results (HPLC method):

See Table 1

Transformation products:

not specified

Table 1:

	Test item, beginning of elution			Test item, end of elution
Measurement No.	k	log k	log KOC	log KOC	log k	log KOC
1	1.76	0.25	2.22	2.56	0.41	3.18
2	1.80	0.26	2.28	2.58	0.41	3.18
	log KOCmean		2.25	log KOCmean		3.18
	Standard deviation		0.042	Standard deviation		0.000

Validity criteria fulfilled:

yes

Conclusions:

Using the HPLC method, the following adsorption coefficients were determined for the test item:
2.25 < log KOC < 3.18.

Key value for chemical safety assessment

Koc at 20 °C:

2.72