Registration Dossier
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EC number: 219-552-0 | CAS number: 2460-77-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- 1. SOFTWARE
Danish QSAR database's EPI ECOSAR
2. MODEL (incl. version number)
v1.11
3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL
C(C)(C)(C)C1C(=O)C=C(C(C)(C)C)C(=O)C=1
4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
[Explain how the model fulfils the OECD principles for (Q)SAR model validation. Consider attaching the QMRF or providing a link]
- Defined endpoint: Green alage 96 hour growth inhibition - Qualifier:
- no guideline available
- Principles of method if other than guideline:
- - Software tool(s) used including version:
Danish QSAR database's EPI ECOSAR
- Model(s) used: 1.11
- Model description: see field 'Justification for non-standard information'
- Justification of QSAR prediction: see field 'Justification for type of information', 'Attached justification' and/or 'Cross-reference' - GLP compliance:
- not specified
- Specific details on test material used for the study:
- CAS 2460-77-7
- Key result
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.04 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Conclusions:
- The QSAR prediction by the Danish QSAR database etimates that the 96 hour EC50 is 0.04.
- Executive summary:
The QSAR prediction by the Danish QSAR database etimates that the 96 hour EC50 is 0.04.
Reference
Description of key information
The QSAR prediction by the Danish QSAR database etimates that the 96 hour EC50 is 0.04.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.04 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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