Registration Dossier
Registration Dossier
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EC number: 202-594-9 | CAS number: 97-61-0
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source. Test conditions not in accordance with current test guidelines (test volume; concentration of test material; readings; score; observation period). Documentation insufficient.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
- Principles of method if other than guideline:
- Method: other: no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-methylvaleric acid
- EC Number:
- 202-594-9
- EC Name:
- 2-methylvaleric acid
- Cas Number:
- 97-61-0
- Molecular formula:
- C6H12O2
- IUPAC Name:
- 2-methylpentanoic acid
Constituent 1
Test animals / tissue source
- Species:
- rabbit
Test system
- Vehicle:
- not specified
- Amount / concentration applied:
- Concentration: 5 % active substance
Amount applied: 0.25 ml - Details on study design:
- Comment: not rinsed
Results and discussion
Any other information on results incl. tables
Irritation symptoms included necrosis of the cornea.
Applicant's summary and conclusion
- Conclusions:
- Invalid study.
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