[μ-(5-amino-1,3,3-trimethylcyclohexylamine-N:N')]hexafluorodiboron

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

This study was conducted between 23 September 2016 and 23 March 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study is considered to be a reliability 1 as it has been conducted according to OECD TG 105 using the column elution method and in compliance with GLP.

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

EC NO. 440/2008 of 30 May 2008

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Specific details on test material used for the study:

Identification : μ(5-amino-1,3,3-trimethylcyclohexylamine-N,N')hexafluorodiboron
Appearance/Physical state: Clear colorless liquid
Batch : AEF0009100
Purity : 51.8%
Expiry date : 29 August 2017
Storage conditions: Room temperature, in the dark.

Key result

Water solubility:

< 95 vol%

Conc. based on:

test mat.

Temp.:

20 °C

pH:

> 4 - < 5.5

Remarks on result:

not determinable because of methodological limitations

The results of the definitive test for the water solubility are shown in the following table:

Table 1

Concentration (% w/w)	Observation	pH
5.05	Clear colorless solution free from any excess test item	4.0
10.0	Clear colorless solution free from any excess test item	4.2
30.1	Clear colorless solution free from any excess test item	4.6
49.9	Clear straw colored solution free from any excess test item	5.1
74.6	Clear straw colored solution free from any excess test item	5.4
79.7	Clear straw colored solution free from any excess test item	5.5
89.8	Clear straw colored solution free from any excess test item	5.4
94.6	Clear straw colored solution free from any excess test item	5.2

Water solubility greater than 95 %w/w at 20.0 ± 0.5 ºC. 

Discussion

The standard EC Method A6 and OECD Method 105 was not applicable to this test item due to the high indeterminable saturation levels produced. It was therefore not possible to prepare samples at five times the saturation level as recommended in the guidelines. No analysis could be performed for the main test due to the high solubility producing unfilterable mixtures. Therefore the water solubility was determined based on visual inspection.

Conclusions:

The water solubility of the test item has been determined to be greater than 95% w/w of solution at 20.0 ± 0.5 ºC. Equivalent to 4.8057 g per 0.2752 g water and therefore water solubility is 17.46 g/mL

Executive summary:

The general physico-chemical properties of μ(5-amino-1,3,3-trimethylcyclohexylamine-N,N')hexafluorodiboron have been determined. 

Water Solubility. Determined to be greater than 95% w/w of solution at 20.0 ± 0.5 ºC, using a flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995

Equivalent to 4.8057 g per 0.2752 g water and therefore water solubility is 17.46 g/mL

Key value for chemical safety assessment

Water solubility:

17 462 573 mg/L

at the temperature of:

20 °C