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Reaction mass of Cobaltate(2-), [2-[[[4-hydroxy-3-[[2-oxo-1-[(phenylamino)carbonyl]propyl]azo]phenyl]sulfonyl]amino]benzoato(3-)][2-[[2-hydroxy-5-[(phenylamino)sulfonyl]phenyl]azo]-3-oxo-N-phenylbutanamidato(2-)]-, disodium and Cobaltate(3-), bis[2-[[[4-hydroxy-3-[[2-oxo-1-[(phenylamino)carbonyl]propyl]azo]phenyl]sulfonyl]amino]benzoato(3-)]-, trisodium and sodium bis[2-[[2-hydroxy-5-[(phenylamino)sulphonyl]phenyl]azo]-3-oxo-N-phenylbutyramidato(2-)]cobaltate(1-)
EC number: 947-257-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Remarks:
- source of read across
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: daphnia.
- Age of organisms: <72 hours of age.
BREEDING
- Breeding conditions: animals are bred under temperature - and light- controlled conditions in water containing sufficient microorganisms. Temperature 21 ± 2 °C; light from 06:00 am to 6:00 pm (12 h light/dark cycle).
- Water: breeding water is prepared with 0.2 g of NaHCO3, 0.224 g of CaCl2, 0.026 g of K2SO4 filled up with distilled water to 1000 ml. Alternate: “Evian” water.
- Feeding frequency: 2 or 3 times a week. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Test temperature:
- Vessels: 21 °C
Control: 21 °C - pH:
- Vessels: 7.6 - 7.8
Control: 7.6 - 7.7 - Dissolved oxygen:
- Vessels:saturated - 96 %
Control: saturated - 99 % - Nominal and measured concentrations:
- Nominal concentrations : 0.1,1.0, 10 and 100 mg/l
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 5 daphnids.
- No. of vessels per concentration: 2 replicates.
- No. of vessels per control: 2 replicates.
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: test tubes are filled with 9 ml of “Evian” water each.
EFFECT PARAMETERS MEASURED
After 24h and 48h respectively mobile (living) daphnids are counted. - Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- No immobilization was noted in all the test concentrations at the end of 48 h exposure period.
- Conclusions:
- EC50 (48h) > 100 mg/l (nominal)
- Executive summary:
Toxicity of test substance was estimated according to OECD test guideline 202. Five daphnids in duplicate sets per test concentration were exposed to 0.1, 1.0, 10 and 100 mg/l concentration . No immobilization was noted in all the test concentrations at the end of 48 h exposure period; therefore, the 48 h EC50 was found to be greater than 100 mg/l.
Conclusion
EC50 (48h) > 100 mg/l (nominal)
Reference
OVERALL IF RESULTS
Nominal concentrations (mg/l) |
No. of animals | No. of immobilized Dapnhia (24 h) | No. of immobilized Dapnhia (48 h) | % immobility (24 h) | % immobility (48 h) |
Vehicle | 5 + 5 | 0 | 0 | 0 | 0 |
Blank | 5 + 5 | 0 | 0 | 0 | 0 |
0.1 | 5 + 5 | 0 | 0 | 0 | 0 |
1.0 | 5 + 5 | 0 | 0 | 0 | 0 |
10 | 5 + 5 | 0 | 0 | 0 | 0 |
100 | 5 + 5 | 0 | 0 | 0 | 0 |
TEST CONDITIONS
Nominal conc. (mg/l) | Start | End | |||||
100 | Vehicle | Blank | 0.1 | 1 | 10 | 100 | |
Oxygen (%) | Saturated | 99 | 99 | 97 | 97 | 97 | 96 |
pH | 7.6 | 7.7 | 7.7 | 7.8 | 7.8 | 7.8 | 7.8 |
Temperature (°C) | 21 | 21 | 21 | 21 | 21 | 21 | 21 |
Description of key information
Not harmful/toxic for invertebrates (EC50 (48h) > 100 mg/l (nominal))
Key value for chemical safety assessment
Additional information
There is no information about the short-term toxicity to invertebrates of Acid Yellow 235, thus the available data on structural analogous Similar Substance 01 has been taken into account. The read across approach can be considered as reliable and adequate for the purpose; details and explanations are detailed in the report attached to the IUCLID section 13.2.
Toxicity of Similar Substance 01 was estimated according to OECD test guideline 202. Five daphnids in duplicate sets per test concentration were exposed to 0.1, 1.0, 10 and 100 mg/l concentration . No immobilization was noted in all the test concentrations at the end of 48 h exposure period; therefore, the 48 h EC50 was found to be greater than 100 mg/l.
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