2,3-epoxypropyl isopropyl ether

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

other: publication

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Peer reviewed handbook

Principles of method if other than guideline:

peer reviewed handbook data, no information is given on test method

GLP compliance:

not specified

Type of method:

other: not specified

Boiling pt.:

137 °C

Atm. press.:

760 mm Hg

Conclusions:

Boiling point = 137°C (at 760 mm Hg)

Executive summary:

For the substance isopropyl glycidyl ether a boiling point of 137°C at 760 mm Hg is reported .

Description of key information

Boiling Point:
1) 137°C (760 mm Hg; handbook data)
2) 131°C (no information on atm. pressure available; peer-reviewed internet database)
3) 137-138°C (No data available for atm. pressure; Authoritative secondary source)
4) 137°C (No data available for atm. pressure; Authoritative secondary source)
5) 137°C (No data available for atm. pressure; Authoritative secondary source)
6) 131-134°C (No data available for atm. pressure; Authoritative secondary source)
7) 131-132°C (760 Torr; Authoritative secondary source)
8) 90-100°C (5 Torr; Authoritative secondary source)
9) 68°C (65 Torr; Authoritative secondary source)
10) 131°C (760 Torr; QSAR estimation using ACD Labs software v11.02)
11) 116.99°C (760 mm Hg, QSAR estimation, MPBPWIN v1.43 (EPIWIN software) by US-EPA (2012), supporting study)

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

137 °C

Additional information

There are several published values available from handbooks or internet databases, all assessed with reliability 2, in the range of 131 -138°C, three of them confirmed to be measured at atmospheric pressure. Hence, it can be concluded that the other values were also derived at atmospheric pressure, leading to the implication that the real value can be taken as 131°C at 760 Torr.

Further values are available in the temperature range of 68 -100°C, measured at a pressure of 5 -65 Torr. Since these low values are generally less relevant for risk assessment, where the usual atmospheric pressure of 1.013 bar is relevant, these values can so be regarded to a lesser extent, which is also applicable for the two values derived from QSAR estimation. Hence, 137°C at 760 Torr are left as the proper value for further risk assessment.