Ammonium iron(III) citrate

Density

Link to relevant study record(s)

Reference

Endpoint:

bulk density

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard test guidelines

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Qualifier:

according to guideline

Guideline:

other: Adopted from method recommended in the International Pharmacopoeia, fourth Edition, 2014

GLP compliance:

no

Type of method:

pour and tap (for solids)

Key result

Type:

density

Density:

1.064 g/cm³

Temp.:

26 °C

Remarks on result:

other: Density was observed at 978.0 hPa.

TEST CHEMICAL DESCRIPTION AND RESULTS :

FOR SOLIDS:

By Pour Density and Tapped Density Method:

Method Details		Observations		Remarks if, any
Guideline	OECD 109	1st Reading	2nd Reading
Method	Test methods: Pour density and tapped density of powders” recommended in The International Pharmacopoeia, Fourth Edition, 2014
Principle of method	Pour Density: It is the ratio of known weight of test item and its volume in graduated glass cylinder. Tap Density: It is the difference between the volume of test item measured before & after tapping in the graduated glass cylinder.
Test temperature (°C)		26°C	26°C
Atmospheric pressure (in hPa)		978.1 hPa	977.9 hPa
Weight of test item(m)		20.167 g	20.159 g
Volume of measuring cylinder; readability in g		50 ml;1ml	50 ml;1ml
Volume of test item without tapping (V)		18 g	20 g
Volume of test item after tapping ( V1)	After 10 tapping	17 g	19 g
	After 50 tapping	16 g	18 g
	After 100 tapping	16 g	18 g
	After 250 tapping	-	-
	After 500 tapping	-	-
	After 750 Tapping	-	-

CALCULATIONS:

FOR SOLIDS:

By Pour Density and Tapped Density Method:

Parameters	Details	Calculated values		Average Density
		1st Calculation	2nd Calculation
Pour Density of test Item (g/cm³)	= m V	1.1203	1.0079	1.0641
Tap density of test Item (g/cm³)	= m V1	1.2604	1.1199	1.1901

Conclusions:

The mean pour density and tapped density of test chemical was determined to be 1.0641 g/cm³ and 1.1901 g/cm³ at 26 °C and 978.0 hPa.

Executive summary:

A study was performed to determine the density of test chemical in respective atmospheric pressure and temperature conditions. The study was conducted in accordance with OECD guideline for the Testing of Chemicals no. 109; Density of Liquid and Solids and Adopted from method recommended in the International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of test chemical was determined to be 1.0641 g/cm³ and 1.1901 g/cm³ at 26 °C and 978.0 hPa.

Description of key information

A study was performed to determine the density of test chemical in respective atmospheric pressure and temperature conditions. The study was conducted in accordance with OECD guideline for the Testing of Chemicals no. 109; Density of Liquid and Solids and Adopted from method recommended in the International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of test chemical was determined to be 1.0641 g/cm³ and 1.1901 g/cm³ at 26 °C and 978.0 hPa.

Key value for chemical safety assessment

Relative density at 20C:

1.06

Additional information

A study was performed to determine the density of test chemical in respective atmospheric pressure and temperature conditions. The study was conducted in accordance with OECD guideline for the Testing of Chemicals no. 109; Density of Liquid and Solids and Adopted from method recommended in the International Pharmacopoeia, fourth Edition, 2014. The mean pour density and tapped density of test chemical was determined to be 1.0641 g/cm³ and 1.1901 g/cm³ at 26 °C and 978.0 hPa.

Based on the data obtain from various handbooks and authoritative databases, the density of test chemical was determined to be 1.8 g/cm³ at temperature 20 °C.