Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 245-396-8 | CAS number: 23047-25-8
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- other: QSAR model
- Title:
- Developmental/Reproductive Toxicity library (PG) 1.0.0
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
Test material
- Details on test material:
- The SMILES included in the reference substance linked in Section 1 (General information) was used as model input.
Results and discussion
Results (fetuses)
- Details on embryotoxic / teratogenic effects:
- Toxic to development.
Any other information on results incl. tables
The subsance is included in the training set of the QSAR - PG model as toxic to development
Applicant's summary and conclusion
- Conclusions:
- Experimental value is Toxicant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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