Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-181-3 | CAS number: 92-71-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24th July 2017 to the 20th November 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Qualifier:
- according to guideline
- Guideline:
- other: European Commission Guidance Document EUR 20268 ‘Determination of Particle Size Distribution, Fibre Length and Diameter Distribution of Chemical Substances’ (2002).
- Principles of method if other than guideline:
- Intended to provide a procedure for the study of the airborne dust and the nature of the dust produced for water soluble compounds.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- cascade impaction
- Type of particle tested:
- primary particle
Test material
- Reference substance name:
- 2,5-diphenyloxazole
- EC Number:
- 202-181-3
- EC Name:
- 2,5-diphenyloxazole
- Cas Number:
- 92-71-7
- Molecular formula:
- C15H11NO
- IUPAC Name:
- 2,5-diphenyl-1,3-oxazole
- Test material form:
- solid: crystalline
- Details on test material:
- Expiry date:01 February 2021
Storage conditions: Room temperature in the dark
Batch 21-16131
1
- Specific details on test material used for the study:
- Identification:
2,5-diphenyloxazole
Appearance/Physical state:
White crystalline powder
Batch:
21-16131
Purity:
99.9%
Expiry date:
01 February 2021
Storage conditions:
Room temperature, in the dark
Results and discussion
Particle size
- Key result
- Remarks on result:
- not measured/tested
Particle size distribution at different passagesopen allclose all
- No.:
- #1
- Size:
- < 100 µm
- Distribution:
- ca. 60.9 %
- No.:
- #2
- Size:
- < 10 µm
- Distribution:
- < 0.35 %
- No.:
- #3
- Size:
- < 5.5 µm
- Distribution:
- < 0.06 %
Any other information on results incl. tables
The overall results from the cascade impactor were taken as limit values due to the variation between the sampling positions; this gives a worst case scenario.
Too few particles were of a size less than 10.0 μm to allow accurate assessment of the mass median aerodynamic diameter.
Applicant's summary and conclusion
- Conclusions:
- The substance (2,5-diphenyloxazole) particle size was studied in accordance withEuropean Commission Guidance Document EUR 20268 via a GLP-certified laboratory. The study used the cascade impactor method and determined that the substance particle size was 60.9% less than 100 μm, <0.35 % less than 10μm and <0.06 % less than 5.5 μm respectively. Too few particles were of a size less than 10.0 μm to allow accurate assessment of the mass median aerodynamic diameter.
- Executive summary:
The substance (2,5-diphenyloxazole) particle size was studied in accordance withEuropean Commission Guidance Document EUR 20268 via a GLP-certified laboratory. During the determinations, air was drawn through the cascade impactor by a vacuum pump at a flow rate of approximately 60 L/min for approximately 30 seconds. The air flow enters the impactor through a throat and inlet tube and then accelerates through the multiple stages. At each stage one or more nozzles direct the particle-laden airstream into a collection cup.
Particles larger than the cut size of a stage, impact onto the collection plate and stay in the collection cup. Smaller particles follow the airstream and are carried to the next stage. In succeeding stages the nozzles are smaller, the air velocity is higher and finer particles are collected. In the final stage the smallest particles are collected on a glass fibre filter. The mass of the artificial throat, collection cups and filter were recorded before and after each determination. The overall results from the cascade impactor were taken as limit values due to the variation between the sampling positions; this gives a worst case scenario.
The study used the cascade impactor method and determined that the substance particle size was 60.9% less than 100 μm, <0.35 % less than 10μm and <0.06 % less than 5.5 μm respectively. Too few particles were of a size less than 10.0 μm to allow accurate assessment of the mass median aerodynamic diameter.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.