Registration Dossier
Registration Dossier
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EC number: 611-645-8 | CAS number: 58349-17-0
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Remarks:
- Eye
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 15th January 1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Materials and methods
Test material
- Specific details on test material used for the study:
- To provide information on health hazards likely to arise from a single instillation of (S)-5-Methoxy-2-aminotetralin into the eyes of rabbits.
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
- Sex:
- male/female
Administration / exposure
- Route of administration:
- other: Added into the eye
- Doses:
- 0.06 g
- No. of animals per sex per dose:
- 2 males and 1 female
Results and discussion
- Mortality:
- All three were found dead within 1 hour of dosing.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
