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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 201-283-5 | CAS number: 80-48-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Eye Contact: Check for and remove any contact lenses. DO NOT use an eye ointment. Flush eyes with running water for a minimum of 15 minutes, occasionally lifting the upper and lower eyelids. Seek medical attention. Treat symptomatically and supportively.
Skin Contact: If the chemical gets spilled on a clothed portion of the body, remove the contaminated clothes as quickly as possible, protecting your own hands and body. Place the victim under a deluge shower. If the chemical touches the victim's exposed skin, such as the hands: Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Seek medical attention. Treat symptomatically and supportively. Wash any contaminated clothing before reusing.
Inhalation: If the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not improve.
Ingestion: INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not re-enter the mouth and throat. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive.
Fire-fighting measures
Combustion Products: These products are toxic carbon oxides (CO, CO 2), sulfur oxides (SO2, SO3...).
Fire Hazards: Reactive with strong oxidizers. Vapors may travel to source of ignition and flash back. Closed containers may explode from the heat of a fire. Highly flammable in presence of open flames and sparks, of heat.
Explosion Hazards:
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
No additional information is available regarding the risks of explosion.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemicals, CO2, water spray or foam.
LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
Consult with local fire authorities before attempting large scale fire-fighting operations.
Accidental release measures
Spill Clean-up Instructions:
Irritating liquid. Toxic liquid. Carcinogenic material. Sensitizing material.
Stop leak if without risk. If the product is in its solid form: Use a shovel to put the material into a convenient waste disposal container. If the product is in its liquid form: DO NOT get water inside container. Absorb with an inert material and put the spilled material in an appropriate waste disposal. DO NOT touch spilled material. Use water spray to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all sources of ignition.
Consult federal, state, and/or local authorities for assistance on disposal.
Handling and storage
Handling and Storage Information:
TOXIC. IRRITANT. CARCINOGEN. SENSITIZER. Handle with caution and minimize exposure. Keep container dry. Keep away from heat and sources of ignition. Mechanical exhaust required.
When not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. DO NOT ingest. DO NOT breathe dust. Never add water to this product. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label.
Treat symptomatically and supportively. Avoid contact with skin and eyes.
Always store away from incompatible compounds such as oxidizing agents.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, N.O.S.
- Chemical name:
- p-Toluenesulfonic Acid Methyl Ester
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, N.O.S.
- Chemical name:
- p-Toluenesulfonic Acid Methyl Ester
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, N.O.S.
- Chemical name:
- p-Toluenesulfonic Acid Methyl Ester
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2811
Shipping information
- Proper shipping name and description:
- Toxic solid, organic, N.O.S.
- Chemical name:
- p-Toluenesulfonic Acid Methyl Ester
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Personal Protection: Splash goggles. Lab coat. Vapor and dust respirator. Boots. Gloves.
A MSHA/NIOSH approved respirator must be used to avoid inhalation of the product.
Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Exposure Limits: This chemical is classified as a possible carcinogen. There is no acceptable exposure limit for a carcinogen.
Stability and reactivity
Stability: This material is stable if stored under proper conditions.
Conditions of Instability: Avoid excessive heat and light. Flammable.
Incompatibilities: Reactive with strong oxidizing agents, strong acids, and strong alkalis (bases).
Disposal considerations
Recycle to process, if possible. Consult your local or regional authorities. You may be able to dissolve or mix material with a combustible solvent and bum in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state, and local regulations when disposing of this substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.