Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
not specified
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: information lacking, insufficient for assessment

Data source

Reference
Reference Type:
secondary source
Title:
ChemIDplus CAS 99-91-2
Bibliographic source:
"Manual of Pharmacology and Its Applications to Therapeutics and Toxicology," 8th ed., Sollman, T., Philadelphia, W.B. Saunders Co., 1957 Vol. 8, Pg. 192, 1957.

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4'-chloroacetophenone
EC Number:
202-800-7
EC Name:
4'-chloroacetophenone
Cas Number:
99-91-2
Molecular formula:
C8H7ClO
IUPAC Name:
1-(4-chlorophenyl)ethan-1-one
Test material form:
not specified
Details on test material:
test material
Specific details on test material used for the study:
The respective test substance is not specified as to its chemical form.

Results and discussion

Applicant's summary and conclusion

Executive summary:

Test type: human TCLo

Route: Inhalation

Reported dose (normalized dose): 1mg/m3/1M (1mg/m3)

Effect: SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE