Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 815-966-6 | CAS number: 915972-17-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
Short-term toxicity
In a 14-day acute toxicity study (IBACON, 394408, 2011) with Eisenia fetida according to OECD 207 (1984), the LC50 of the test substance with Eisenia fetida was > 1000 mg/kg dry soil.
Long-term-toxicity
In a 56 day chronic test (BASF SE, 394409, 2012) with Eisenia fetida according to OECD 222 (2004) the test substance caused no adverse effects on survival, biomass development and reproduction of parent earthworms up to and including the highest concentration of 473 mg/kg dry soil. The overall NOEC for weight change, survival and reproduction was equivalent to 473 mg/kg soil dry weight. The EC50 for reproduction is 804.39 mg/kg soil dry weight (> highest concentration tested).
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 473 mg/kg soil dw
Additional information
Short-term toxicty
In a 14-day acute toxicity study (IBACON, 394408, 2011) with Eisenia fetida, earthworms were exposed to the test substance according to OECD 207 (1984) for 14 days in artificial soil (OECD 207 substrate with 5% organic matter). The test was conducted in 1 L glass bottle jars covered with a glass lid, containing 500 g artificial dry soil. The untreated control and nominal test item concentrations of 198, 296, 444 667 and 1000 mg/kg dry soil were tested with 4 replicates containing 10 worms each. The vessels were maintained at 18.0 - 22.0 °C under continuous light. After 14 days of exposure, no mortality was observed in the control or any test item concentration. The body weight changes were not statistically significantly different compared to the control up to and including the highest concentration of 1000 mg/kg dry soil. No behavioral effects were observed. The LC50 of the test substance with Eisenia fetida was > 1000 mg/kg dry soil.
In addition in a 14 -d toxicity study (BioChem agrar, 394877, 2014) to earthworms (Eisenia fetida) according to OECD 207 (1984) with the metabolite (M440I002) of the registered test substance, the LC50 was estimated to be greater than 1000 mg/kg soil dry weight.
Moreover in a 14-day acute toxicity study (IBACON, 394871, 2014) according to OECD 207 (1984) with the metabolite (M440I003) of the registered test substance to earthworms (Eisenia fetida) the 14-day LC50 was determined to be greater than 1000 mg test item/kg dry soil.
Additionally in a 14-d toxicity study (Labor für biologische und chemische Analytik GmbH, 394883, 2014) to earthworms (Eisenia fetida) with the metabolite (M440I005) of the registered test substance the LC50 was estimated to be greater than 1000 mg/kg soil dry weight.
Additionally in a 14-d toxicity study (IBACON, 735863, 2015) to earthworms (Eisenia fetida) with the metabolite (M440I024) of the registered test substance the LC50 was estimated to be greater than 1000 mg/kg soil dry weight. The NOEC was determined to be ≥ 1000 mg /kg soil dry weight.
Long-term-toxicity
In a 56 day chronic test (BASF SE, 394409, 2012), earthworms (Eisenia fetida) were exposed to the test substance according to OECD 222 (2004) for 28 days in artificial soil (OECD 222 substrate with 5% organic matter). After this period, the adults were removed and cocoons remained in the test vessels for an additional 28 days. The test was conducted in1 L plastic dishes covered with transparent and punctured lids, containing 600 g artificial dry soil. Soil concentrations of29.54, 59.1, 118, 236 and 473 mg/kg dry soil (corresponding to nominal concentrations of 31.25, 62.5, 125, 250 and 500 mg/kg dry soil) were tested in 4 replicates of 10 worms each. Additionally, an untreated control with 8 replicates each containing 10 worms was included. The vessels were maintained at 19 – 21 °C under a 16 hours light (400-800 lux) and 8 hours dark photoperiod. Soil moisture was maintained at 60% of the WHC. No mortality of parent earthworms was observed in the control and any of the treatment groups up to and including the highest concentration of 473 mg/kg soil dry weight. Body weight change of the earthworms exposed to the test substance was not statistically significantly different compared to the control up to and including the highest test item concentration of 473 mg/kg soil dry weight. The feeding activity of the earthworms was not reduced up to and including the highest concentration of 473 mg per kg soil dry weight. No other behavioral abnormalities were observed in any of the treatment groups. Reproduction was not statistically different compared to those in the control up to and including the highest test concentration of 473 mg/kg soil dry weight. The overall NOEC for weight change, survival and reproduction was equivalent to 473 mg/kg soil dry weight. The EC50 for reproduction is 804.39 mg/kg soil dry weight (> highest concentration tested).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.