Registration Dossier
Registration Dossier
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EC number: 254-487-1 | CAS number: 39515-51-0
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Test procedure in accordance with national standard methods with acceptable restrictions.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 977
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- m-phenoxybenzaldehyde
- EC Number:
- 254-487-1
- EC Name:
- m-phenoxybenzaldehyde
- Cas Number:
- 39515-51-0
- Molecular formula:
- C13H10O2
- IUPAC Name:
- 3-phenoxybenzaldehyde
- Details on test material:
- No information on purity available
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- unchanged (no vehicle)
- Duration of exposure:
- 24 hours
- Doses:
- 0.464, 1.00, 2.15, 4.64 mL/kg bw
- No. of animals per sex per dose:
- 4
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 4.64 mL/kg bw
- Based on:
- test mat.
- Mortality:
- No mortalities occurred at any dosage level tested.
- Clinical signs:
- other: diarrhea, emaciation, irritative effects incl. slight spotty to moderate erythema, desquamation at the application site, nasal discharge, oily unkempt fur around the exposure site
- Gross pathology:
- No other gross pathological alterations were observed.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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