Diammonium 5-(hexylsulfonyl)-2-{[3-methyl-2,7-dioxo-1-(3-sulfonatobenzoyl)-2,7-dihydro-3H-naphtho[1,2,3-de]heterocycle-6-yl]amino}benzenesulfonate

Surface tension

Administrative data

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08 January 2009 to 26 February 2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

yes

Remarks:

This deviation has been considered not to have affected the integrity of the study.

Principles of method if other than guideline:

The determination was carried out using a White Electrical Institute interfacial tension balance and a procedure based on the ISO 304 ring method. With the exception of the following deviation, the experimental procedure used complied with that specified in Method A5 Surface Tension of Commission Regulation (EC) No 440/2008 of 30 May 2008.
1) The surface tension result was not corrected using the Harkins-Jordan correction table as the correction is not applicable to the apparatus used. Once calibrated, the balance and ring assembly used in this test give a direct reading for surface tension that is within the required accuracy (± 0.5 mN/m); this is as a result of the reduced ring dimensions.

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of inspection: 19 August 2008; Date of signature: 04 March 2009

Type of method:

ring method

Test material

Test material information

Results and discussion

Surface tension

Surface tension:

70 mN/m

Temp.:

21.2 °C

Conc.:

1.05 g/L

Any other information on results incl. tables

Calibration factor (f)

The readings, temperatures and the corresponding calibration factors for glass double-distilled water are shown in the following table:

Table 2

Reading (mN/m)	Temperature (ºC)	Literature Value (mN/m)	Calibration Factor
72.5	21.2	72.53	1.000
72.5	21.2	72.53	1.000
72.5	21.2	72.53	1.000
72.5	21.2	72.53	1.000
72.5	21.2	72.53	1.000
72.5	21.2	72.53	1.000
Mean Calibration Factor = 1.000

Sample solution readings

The readings, times and temperatures for the sample solution are shown in the following table:

Table 3

Time (mins)	Reading (mN/m)	Temperature (ºC)
105	70.0	21.2
115	70.0	21.2
140	70.0	21.2
150	70.0	21.2
160	70.0	21.2

Mean reading                 :   70.0 mN/m
Surface tension              = reading x calibration factor
                                         = 70.0 x 1.000
                                         = 70.0 mN/m
Temperature                   :   21.2 ± 0.5ºC
pH of sample solution    :   6.2

Applicant's summary and conclusion

Conclusions:

The surface tension of a 1.05 g/l solution of test material has been determined to be 70.0 mN/m at 21.2 ± 0.5°C. The test material is considered not to be a surface-active material.

Executive summary:

70.0 mN/m (1.05 g/l solution) at 21.2 ± 0.5°C, using a ring method based on ISO 304, Method A5 Surface Tension of Commission Regulation (EC) No 440/2008 of 30 May 2008.