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Diss Factsheets
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EC number: 259-452-4 | CAS number: 55039-14-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Data are available on Similar substance 01:
EC50 (48h) invertebrate Daphnia: > 100 mg/L
NOEC (48h) invertebrate Daphnia: 69 mg/L
EC50 (96h) Growth rate Frond Number Lemna: 69 mg/L
TL50 6.5 mg/L.
Additional information
Short-term toxicity to aquatic invertebrates
A study was performed to assess the acute toxicity of the test item to Daphnia magna. Test organism were exposed to an aqueous solution of the Similar substance 01 at concentrations of 0.1, 1.0, 10.0 and 100 mg/L for 48 hours at a temperature of 20 °C to 22 °C under static test conditions (no guideline available). There was no significant immobilization in 20 daphnids exposed to a maximum test concentration of 100 mg/L for a period of 48 hours. Hence, the 48 hour EC50 and NOEC values were determined to >100 mg/L and 100 mg/L, respectively.
Based on the read across principle(read-across from supporting substance -structural analogue or surrogate), the results can be considered assessment of the registered substance.
Justification for read across is detailed in the report attached to the IUCLID section 13.
Toxicity to aquatic plants other than algae
A study was performed to assess the effect of the test item on the growth of the freshwater plant Lemna minor. The method followed that described in the OECD Guideline No. 221 “Lemna sp. Growth Inhibition Test (March 2006)”.
Exposure of Lemna minor to the test item gave the following results based on the geometric mean measured test concentrations:
EC50 (mg/L) Growth rate Frond Number: 69
EC50 (mg/L) Growth rate Dry weight: > 86 *
EC50 (mg/L) Yield Frond number 3.9
EC50 (mg/L) Growth rate Dry weight: 3.2
NOEC (mg/L): 0.75
LOEC (mg/L): 2.7
* It was not possible to calculate an ErC50 value as no concentration tested resulted in 50% inhibition of growth rate.
Based on the read across principle(read-across from supporting substance -structural analogue or surrogate), the results can be considered assessment of the registered substance.
Justification for read across is detailed in the report attached to the IUCLID section 13.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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