Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-477-1 | CAS number: 65122-06-7
Endpoint summary
Administrative data
Description of key information
LC50 (96h) in fish = 266 mg/l
EC50 (48h) in aquatic invertebrates = 37.1 mg/l
EC50 (7d) in aquatic plants other than algae = 7.46 mg/l as for growth rate of frond number and ErC50 = 5.91 mg/l as for growth rate of dry weight.
Additional information
Justification for classification or non-classification according to the CLP Regulation (EC 1272/2008)
The threshold of classification of a substance for acute aquatic toxicity is 1 mg/l. This limit is compared with LC50 (96h) for fish, EC50 (48 h) for daphnia and EC50 (72 - 96 h) for algae or other aquatic plants.
The classification process relied on data of toxicity to fish, aquatic invertebrates, i.e. daphnia, and aquatic plants, i.e. lemna.
As for fish, available 96 -hour study showed an LC50 value of 250 mg/l.
As for daphnia, acute immobilisation was seen in 50 % of daphnia exposed for 48 hours at a concentration of 48.9 mg/l.
As for lemna, a 7 -day exposure caused effects on growth rate of frond number and dry weight with ErC50 = 7.46 mg/l and ErC50 = 5.91 mg/l, respectively.
No chronic toxicity data is available from long-term studies. In case of lack of chronic data, the potential for chronic toxicity is identified by appropriate combinations of acute toxicity data and lack of biodegradability. Classification is applied as follows:
- category 1 for EC50 and/or LC50 < 1 mg/l
- category 2 for EC50 and/or LC50 = 1 - 10 mg/l
- category 3 for EC50 and/or LC50 = 10 - 100 mg/l.
- safety net or no classification above 100 mg/l.
Based on available results, lemna appeared as the most sensitive species and implied a classification in Category 2 for chronic aquatic toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
