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EC number: 204-541-5 | CAS number: 122-40-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from J-check authoritative databases
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- Principles of method if other than guideline:
- Acute toxic effect on the Daphnia magna was observed by using the chemical alpha-Amyl cinnamaldehyde.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): α-Amyl Cinnamaldehyde
- Molecular formula (if other than submission substance): C14H18O
- Molecular weight (if other than submission substance): 202.2952 g/mol
- Substance type: Organic
- Physical state: No data
- Purity: No data
- Impurities (identity and concentrations): No data - Analytical monitoring:
- not specified
- Details on sampling:
- No data
- Vehicle:
- not specified
- Details on test solutions:
- No data
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- No data
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 21 d
- Remarks on exposure duration:
- No data
- Post exposure observation period:
- No data
- Hardness:
- No data
- Test temperature:
- No data
- pH:
- No data
- Dissolved oxygen:
- No data
- Salinity:
- No data
- Conductivity:
- No data
- Nominal and measured concentrations:
- Nominal
- Details on test conditions:
- No data
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 0.054 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- immobilisation
- Key result
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.041 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- immobilisation
- Details on results:
- No data
- Results with reference substance (positive control):
- No data
- Reported statistics and error estimates:
- No data
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Based on the 0.054 mg/l EC50 and 0.041mg/l NOEC value, it can be concluded that the test chemical alpha-Amyl cinnamaldehyde can be considered as toxic to the aquatic organism daphnia at environment revelent concentration and thus can be considered to be classified in aquatic chronic category 2 as per the classification criteria.
- Executive summary:
Long term toxic effect on the Daphnia magna was observed by using the chemical alpha-Amyl cinnamaldehyde with the exposure of 21 days. The EC50 value and NOEC concentration obtain from the test was 0.054 mg/l and 0.041 mg/l.
Based on the 0.054 mg/l EC50 and 0.041mg/l NOEC value, it can be concluded that the test chemical alpha-Amyl cinnamaldehyde can be considered as toxic to the aquatic organism daphnia at environment revelent concentration and thus can be considered to be classified in aquatic chronic category 2 as per the CLP classification criteria.
Reference
Description of key information
Long term toxic effect on the Daphnia magna was observed by using the chemical alpha-Amyl cinnamaldehyde with the exposure of 21 days. The EC50 value and NOEC concentration obtain from the test was 0.054 mg/l and 0.041 mg/l.
Based on the 0.054 mg/l EC50 and 0.041mg/l NOEC value, it can be concluded that the test chemical alpha-Amyl cinnamaldehyde can be considered as toxic to the aquatic organism daphnia at environment revelent concentration and thus can be considered to be classified in aquatic chronic category 2 as per the CLP classification criteria.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.041 mg/L
Additional information
Based on the experimental key study (J-check authoritative databases, 2016) long term toxic effect on the Daphnia magna was observed by using the chemical alpha-Amyl cinnamaldehyde(122 -40 -7) 2 -benzylideneheptanal with the exposure of 21 days. The EC50 value and NOEC concentration obtain from the test was 0.054 mg/l and 0.041 mg/l.Thus on the basis of 0.054 mg/l EC50 and 0.041mg/l NOEC value, it can be concluded that the test chemical alpha-Amyl cinnamaldehyde can be considered as toxic to the aquatic organism daphnia at environment revelent concentration and thus can be considered to be classified in aquatic chronic category 2 as per the CLP classification criteria.
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