Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 605-904-4 | CAS number: 180637-89-2
Guidance on Safe Use
Administrative data
First-aid measures
Eye Contact: Flush eyes continuously with water for at least 15 minutes and obtain immediate medical attention.
Skin Contact: Wash skin with soap and water. If irritation occurs or persists, get medical attention.
Ingestion: In the event of swallowing this material, seek immediate medical attention. DO NOT INDUCE VOMITING. Do not induce vomiting unless directed by medical personnel.
Inhalation: Remove to fresh air. Keep patient at rest. Get medical attention immediately
Fire-fighting measures
Extinguishing Media: Use water spray, foam, dry powder, or carbon dioxide.
Special Hazards Arising from the Substance or Mixture Hazardous Combustion Products:
Emits toxic fumes of carbon monoxide, carbon dioxide, oxides of nitrogen, sulfur oxides, and other sulfur- and bromine-containing compounds
Fire / Explosion Hazards: Very high sensitivity of a dust cloud to ignition, based on minimum ignition energy.
Advice for Fire-Fighters: Wear approved positive pressure, self-contained breathing apparatus and full protective turn out gear
Accidental release measures
Personal Precautions, Protective Equipment and Emergency Procedures: Personnel involved in clean-up should wear appropriate personal protective equipment (see Section 8). Minimize exposure.
Environmental Precautions: Place waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental release.
Methods and Material for Containment and Cleaning Up
Measures for Cleaning /Collecting: Contain the source of the spill if it is safe to do so. Collect spilled material by a method that controls dust generation. Avoid use of a filtered vacuum to clean spills of dry solids, due to the potential for electrostatic discharge and very high sensitivity to ignition. Clean spill area thoroughly.
Additional Consideration for Large Spills:
Non-essential personnel should be evacuated from affected area. Report emergency situations immediately. Clean up operations should only be undertaken by trained personnel.
Handling and storage
Precautions for Safe Handling:
Ground and bond all bulk transfer equipment. Avoid open handling. Minimize dust generation. Use local exhaust ventilation or perform work under fume hood/fume cupboard. Avoid inhalation and contact with skin, eye, and clothing. When handling, use appropriate personal protective equipment (see Section 8). Wash hands and any exposed skin after removal of PPE. Releases to the environment should be avoided. Review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure or environmental releases. Potential points of process emissions of this material to the atmosphere should be controlled with dust collectors, HEPA filtration systems or other equivalent controls.
Conditions for Safe Storage, Including any Incompatibilities
Storage Conditions: Store in airtight and light-resistant containers.
Storage Temperature: Store at room temperature
Specific end use(s): Pharmaceutical process intermediate
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- Not regulated for ADR
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- Not regulated under ADN
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Marine transport (UN RTDG/IMDG)
- UN number:
- Not regulated under IMDG
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- Not regulated under ICAO/IATA
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Exposure controls / personal protection
Pfizer OEL TWA-8 Hr: 0.2 mg/m³, Sensitizer
Exposure Controls
Engineering Controls: Engineering controls should be used as the primary means to control exposures. Use process containment, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits.
Personal Protective Equipment: Refer to applicable national standards and regulations in the selection and use of personal protective equipment (PPE).
Hands: Wear impervious gloves to prevent skin contact.
Eyes: Wear safety goggles as minimum protection.
Skin: Wear impervious protective clothing to prevent skin contact - consider use of disposable clothing where appropriate.
Respiratory protection: If the applicable Occupational Exposure Limit (OEL) is exceeded, wear an appropriate respirator with a protection factor sufficient to control exposures to below the OEL.
Stability and reactivity
Reactivity: No data available
Chemical Stability: Stable at ambient temperatures Stable below 170°C.
Possibility of Hazardous Reactions
Oxidizing Properties: None expected under normal and foreseeable conditions of use
Conditions to Avoid: Light
Incompatible Materials: As a precautionary measure, keep away from strong oxidizers
Hazardous Decomposition Products: None expected under normal conditions.
Disposal considerations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
