Registration Dossier
Registration Dossier
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EC number: 209-636-5 | CAS number: 589-15-1
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vivo (LLNA)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2005
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
- GLP compliance:
- yes (incl. QA statement)
- Type of study:
- mouse local lymph node assay (LLNA)
Test material
- Reference substance name:
- α,4-dibromotoluene
- EC Number:
- 209-636-5
- EC Name:
- α,4-dibromotoluene
- Cas Number:
- 589-15-1
- Molecular formula:
- C7H6Br2
- IUPAC Name:
- α,4-dibromotoluene
Constituent 1
In vivo test system
Test animals
- Species:
- mouse
- Strain:
- CBA/Ca
- Sex:
- not specified
Results and discussion
In vivo (LLNA)
Results
- Parameter:
- SI
- Value:
- >= 12 - <= 22
- Test group / Remarks:
- Considered sensitiser under conditions of test
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (skin sensitising) based on GHS criteria
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