Registration Dossier
Registration Dossier
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EC number: 216-543-3 | CAS number: 1609-66-1
Solubility in organic solvents / fat solubility
Administrative data
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- no data
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient documentation for an assessment of reliability.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
Materials and methods
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- N-phenyl-N-piperidin-4-ylpropionamide
- EC Number:
- 216-543-3
- EC Name:
- N-phenyl-N-piperidin-4-ylpropionamide
- Cas Number:
- 1609-66-1
- Molecular formula:
- C14H20N2O
- IUPAC Name:
- N-phenyl-N-piperidin-4-ylpropionamide
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study reports): JNJ-1594255-AAA (T000425)
- Physical state: solid (powder)
- Appearance: white
Constituent 1
- Specific details on test material used for the study:
- No data
Results and discussion
Solubility in organic solvents / fat solubilityopen allclose all
- Medium:
- methanol
- Solubility:
- > 30 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- ethanol
- Solubility:
- > 30 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- isopropanol
- Solubility:
- > 30 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- other: dichloromethane
- Solubility:
- > 30 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- other: 2-propanone
- Solubility:
- > 30 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- ethyl acetate
- Solubility:
- 19 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- other: 1,1'-oxybisethane
- Solubility:
- 3.7 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- other: hexane
- Solubility:
- 0.49 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- other: methylbenzene
- Solubility:
- 25 other: g/100 mL solution
- Temp.:
- 20 °C
- Medium:
- dimethylformamide
- Solubility:
- > 30 other: g/100 mL solution
- Temp.:
- 20 °C
- Details on results:
- no data
Any other information on results incl. tables
Table 1 Solubility of the T000425 at room temperature
| Solvent | Concentration in g/100 mL solution |
| tetrahydrofuran | >30 |
| 4 -methyl-2-pentanone | 18 |
| sulfinylbismethane | 23 |
| 2 -butanone | 27 |
| 1 -metoxy-2propanol | >30 |
| N,N-dimethylacetamide | >30 |
| 2,2'-oxybispropane | 2.5 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
