Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 289-124-6 | CAS number: 86014-76-8
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
- Report date:
- 1975
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- - Principle of test: single dermal application for LD50 determination.
- Parameters analysed / observed: mortality and gross pathology. - GLP compliance:
- no
- Remarks:
- Pre 1981
Test material
- Reference substance name:
- Iron, complexes with diazotized 2-amino-4,6-dinitrophenol coupled with diazotized 4-nitrobenzenamine and 4-[(2,4-dihydroxyphenyl)azo]-5-hydroxy-2,7-naphthalenedisulfonic acid, sodium salts
- EC Number:
- 289-124-6
- EC Name:
- Iron, complexes with diazotized 2-amino-4,6-dinitrophenol coupled with diazotized 4-nitrobenzenamine and 4-[(2,4-dihydroxyphenyl)azo]-5-hydroxy-2,7-naphthalenedisulfonic acid, sodium salts
- Cas Number:
- 86014-76-8
- Molecular formula:
- n.a.
- IUPAC Name:
- Reaction products of diazotised 4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid coupled with resorcinol, subsequently coupled with diazotized 2-amino-4,6-dinitrophenol and diazotized 4-nitrobenzenamine, chelated with iron (3+), sodium salts
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Vehicle:
- water
- Remarks:
- 50 % preparation
- Details on study design:
- - Observation period: 14 days.
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- > 2 500 mg/kg bw
- Based on:
- test mat.
- Mortality:
- No deaths occurred.
- Gross pathology:
- No abnormalities observed.
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- The substance was tested for acute dermal toxicity following internal guidelines. No details on study design, doses or experimental resulta are available. Howver, a qualiitative LD50> 2500 mg/kb b.w. was determined.
- Executive summary:
The substance was tested for acute dermal toxicity following internal guidelines. No details on study design, doses or experimental resulta are available.Rats were exposed to a single dermal application of the test substance. After 14 days of observation, no deaths occurred and no abnormalities were noted at necropsy.
Conclusion
LD50> 2500 mg/kg b.w.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
