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EC number: 274-397-6 | CAS number: 70209-99-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 10 August, 1993 to 08 December, 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Code number: FAT 92349/A
- Source and batch No.of test material: 56
- Expiration date of the batch: November 1997
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature, protected from light.
- Solubility and stability of the test substance in water: 100 g/L
OTHER SPECIFICS:
- Purity: 68 %
- Appearance: Solid - Analytical monitoring:
- yes
- Details on sampling:
- The concentration of the test substance at the beginning and at the end of the test was analysed by the Analytical Services K, Textile Dyes Division.
All test medium samples for the analytical determinations were taken after mixing of the test solutions from the approximate center of the test vessels and kept at -18 °C to -25 °C until analyses. - Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- STOCK SOLUTION:
0.5 g Test substance were mixed with 200 mL test medium and fill up to 500 mL with test medium. The stock solution was homogenized for five minutes in the supersonics bath. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Source: Laboratories of the Textile Dyes Division, Product Ecology TF
- Age of animals: Animals with age of less than 24 hours were used - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 136 mg/L CaCO3
- Test temperature:
- 21.5 °C (start) , 21.2 °C (end)
- pH:
- 8.0 (start), 7.8 to 7.9 (end)
- Dissolved oxygen:
- saturated (start), 96 - 99 % (end)
- Nominal and measured concentrations:
- The nominal concentrations tested were 10, 18, 32, 58, 100 and 180 mg/L and a control without any additions.
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 250 mL Beakers
- Material, size, headspace, fill volume: 100 - 200 mL test medium
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 2
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Bidistilled water
OTHER TEST CONDITIONS
- Photoperiod: 16 hours light / 8 hours dark
EFFECT PARAMETERS MEASURED: visual assessment of mobility of the daphnids after 24 and 48 hours.
VEHICLE CONTROL PERFORMED: yes - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 194.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- During test duation the test article concentrations in the analysed test media were in the range of 101.2 -109.0 % of the nominal values. Therefore under the test conditions the test article was sufficiently stable.
In all test concentrations no alteration of the test substance after 48 hours was observed. In the control and in the test concentrations up to 107.3 mg/L no immobilization of the daphnids was observed after 48 hours. Therefore, EC50 value could not be calculated. The EC0 value is at least ≥ 107.3 mg/L. The EC50 and EC100 values are higher than 194.6 mg/L. - Results with reference substance (positive control):
- Potassium dichromate (EC50: 0.96 mg/L)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The EC50 values were reported to be higher than 194.6 mg/L.
- Executive summary:
The acute toxicity of FAT 92349/A to Daphnia magna was determined in a 48-hour static test according to the OECD Guideline 202 and EU Method C.2. The nominal concentrations tested were 0 (Control), 10, 18, 32, 58, 100 and 180 mg/L. The reported results are related to the analytical concentrations of the test article. During test duration the test article concentrations in the analysed test media were in the range of 101.2 - 109.0 % of the nominal values. Therefore, under test conditions the test article was sufficiently stable. In all test concentrations no alteration of the test substance after 48 hours was observed. In the control and in the test concentrations up to 107.3 mg/L no immobilization of the daphnids was observed after 48 hours. Therefore, EC50 value could not be calculated. Hence, the EC0 value is at least 107.3 mg/L and the EC50 values were reported to be higher than 194.6 mg/L.
Reference
Description of key information
The acute toxicity of FAT 92349/A to Daphnia magna was determined in a 48-hour static test according to the OECD Guideline 202 and EU Method C.2. The nominal concentrations tested were 0 (Control), 10, 18, 32, 58, 100 and 180 mg/L. The reported results are related to the analytical concentrations of the test article. During test duration the test article concentrations in the analysed test media were in the range of 101.2 - 109.0 % of the nominal values. Therefore, under test conditions the test article was sufficiently stable. In all test concentrations no alteration of the test substance after 48 hours was observed. In the control and in the test concentrations up to 107.3 mg/L no immobilization of the daphnids was observed after 48 hours. Therefore, EC50 value could not be calculated. Hence, the EC0 value is at least 107.3 mg/L and the EC50 values were reported to be higher than 194.6 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 194.6 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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