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EC number: 240-457-5
CAS number: 16409-43-1
Not expected to bioaccumulate in aquatic organisms.
In Article 13 of Regulation (EC) No
1907/2006, it is laid down that information on intrinsic properties of
substances may be generated by means other than tests, provided that the
conditions set out in Annex XI (of the same Regulation) are met.
Furthermore according to Article 25 of the same Regulation testing on
vertebrate animals shall be undertaken only as a last resort.
According to Annex XI of Regulation
(EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific
validity of the (Q)SAR model has been established, (2) the substance
falls within the applicability domain of the (Q)SAR model, (3) the
results are adequate for the purpose of classification and labeling
and/or risk assessment and (4) adequate and reliable documentation of
the applied method is provided.
For the assessment of tetrahydro-4-methyl-2-(2-methylprop-1-enyl)pyran
(Q)SAR results were used for bioaccumulatioin. The criteria listed in
Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately
fulfilled and therefore the endpoint(s) sufficiently covered and
suitable for risk assessment.
Therefore, and for reasons of animal
welfare, further experimental studies on bioaccumulation are not
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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