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EC number: 432-240-0 | CAS number: 12056-51-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing was conducted between 14 January 1999 and 4 May 1999.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Date of inspection: 23/03/1998 Date of signature: 21/07/1998
- Type of method:
- flask method
- Key result
- Water solubility:
- < 0.452 mg/L
- Temp.:
- 20 °C
- pH:
- 6.2
- Remarks on result:
- other: Flask method.
- Water solubility:
- < 0.24 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Visual estimation at room temperature.
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility was determined to be less than 4.52 x 10-4 g/I of solution at 20.0 ± 0.5· C, using the flask method, Method A6 of Commission Directive 92/69/EEC.
By visual estimation, the water solubility was found to be less than 2.40 x 10-4 g/l. - Executive summary:
The water solubility was determined to be less than 4.52 x 10-4 g/L of solution at 20.0 ± 0.5· C, using the flask method, Method A6 of Commission Directive 92/69/EEC.
By visual estimation, the water solubility was found to be less than 2.40 x 10-4 g/l.
- Endpoint:
- water solubility
- Type of information:
- read-across from similar mixture/product
- Adequacy of study:
- key study
- Study period:
- 10th - 19th December 2012
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- - SOP 061.00 Issue No. 6 Expires November 2013 with quantitative measurement by ICP-OES, SOP 025.04 Issue 8 Expires March 2014.
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- 1.4 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: No pH data.
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
- Report:
ASG: 10462612
Water Solubility at 25°C ± 1°C (mg/L): 1.4
Purity of Potassium Hexatitanate was determined by sponsor to be >99% (Batch 180215) - Executive summary:
- Analysts: Joe Wicks (Shake flask Procedure) and Dale Mortimer (ICP-OES Analysis)
- Techniques/lnstrumentation/Test Method Ref/Test Specification Ref:
- Water Solubility in accordance with EU A6 Regulation (EC) No 440/2008, Annex, Official Journal of the European Union, Shake Flask Method.
- SOP 061.00 Issue No. 6 Expires November 2013 with quantitative measurement by ICP-OES, SOP 025.04 Issue 8 Expires March 2014.
- Instrument: Perkin-Elmer Optima 3300 ICP-OES LIMS 0792D (PQ Due: May 2013)
- The data contained in this report has been generated in a laboratory holding a current statement of GLP Compliance, issued by the UK GLP Monitoring Authority, MHRA, but not as part of a formal GLP study.
- Report:
ASG
Water Solubility at 25°C ±1°C (mg/L)
10462612
1.4
Purity of Potassium Hexatitanate was determined by sponsor to be >99% (Batch 180215)
Referenceopen allclose all
- ICP-OES Results: See Table in attached report
- Calculations: The concentration of Potassium and Titanium (mg/I) in each test solution is calculated from the calibration graph using the ICP-OES software.
- Standard Recoveries: Standard recoveries of between 90 -110% for Potassium and Titanium were observed, which are acceptable for analysis at the levels being analysed.
- Treatment of Results:
Timepoint |
K mg/L w/v |
Ti mg/L w/v |
1 Day |
59 |
0.7 |
2 Days |
71 |
0.8 |
3 Days |
70 |
0.6 |
4 Days |
77 |
0.8 |
5 Days |
85 |
0.7 |
For potassium, the solubility does appear to increase with time and the guidelines state repeatability should be <15%. Use of Day 3 to Day 5 results are within the acceptance criteria and therefore the mean of the test 3, 4, and 5 results will be used to calculate the quoted water solubility result. For titanium, there is no clear indication of the solubility changing with time, although at the concentration being observed, it would be difficult to assess. As for potassium, the mean of the test 3, 4, and 5 results will be used to calculate the quoted water solubility result.
Mean of tests 3, 4 and 5 (Total mg/L w/v) 77 mg/I Potassium
Mean of tests 3, 4 and 5 (Total mg/L w/v) 0.7 mg/l Titanium
The titanium content needs to be amended to take into account the composition of the test substance, K2Ti6O13.
Molecular weight K = 38.10
Molecular weight Ti = 47.88
Molecular weight O = 16.00
Molecular weight K2Ti6O13= 573.5
Molecular weight Ti6= 287.3
Therefore 0.7 mg/L Titanium x (573.5/287.3) = 1.4mg/L Potassium Hexatitanate
The potassium content needs to be amended to take into account the composition of the test substance, K2Ti6O13.
Molecular weight K = 38.10
Molecular weight Ti = 47.88
Molecular weight O = 16.00
Molecular weight K2Ti6O13= 573.5
Molecular weight K2 = 76.2
Therefore 77 mg/L Potassium x (573.5/76.2) = 580mg/L Potassium Hexatitanate
The lower values observed for titanium are presumed to reflect the solubility of the test substance Potassium Hexatitanate. The higher concentration of potassium observed may be due to solubte potassium salts in the test substance. A trace amount of soluble potassium salt such as potassium chloride or sulphate in the test substance could result in a significant increase in the potassium content at the levels being observed. The water solubility of Potassium Hexatitanate will be reported as 1.4mg/L. The pH of the aqueous solutions was measured after completion of the tests.
- Individual results:
Test |
pH of solution |
|
|
1 |
7.63 |
2 |
7.65 |
3 |
7.65 |
4 |
7.87 |
5 |
7.87 |
Water blank |
7.89 |
Mean pH of tests 3, 4 and 5 = 7.8
Description of key information
The water solubility of the substance ranges between < 0.454 and 1.4 mg/L at 20 -25 °C.
Key value for chemical safety assessment
- Water solubility:
- 1.4 mg/L
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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