Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation: in vivo (LLNA)
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Study period:
2007
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remarks'
Remarks:
The study as inserted into the disseminated ECHA dossier is a GLP and an OECD guideline study with a structurally similar compound, ethyl trifluoroacetate. This substance is appropriate for read-across as the ethyl group was not known to induce sensitisation.

Data source

Reference
Reference Type:
other: ECHA disseminated dossier
Title:
No information
Report date:
2014

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl trifluoroacetate
EC Number:
206-851-6
EC Name:
Ethyl trifluoroacetate
Cas Number:
383-63-1
Molecular formula:
C4H5F3O2
IUPAC Name:
ethyl trifluoroacetate

Results and discussion

In vivo (LLNA)

Results
Parameter:
SI
Value:
< 1

Applicant's summary and conclusion

Interpretation of results:
not sensitising