Registration Dossier
Registration Dossier
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EC number: 425-320-1 | CAS number: 690-39-1
Endpoint summary
Administrative data
Description of key information
The skin irritation/corrosion and eye irritation studies are not required for gases.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation / corrosion
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The substance is a gas under atmospheric conditions. The performance of eye and skin irritation studies is not technically feasible and scientifically unjustified. Inhalation of excessive concentrations in air may induce symptoms of hypoxia (headache, nausea, dizziness, loss of consciousness) or cardiac sensitization (irregular pulse or arrhythmia). Direct skin contact at point of release may cause symptoms of frostbite due to evaporative cooling (cold, white, discolored skin that, in severe cases, may exhibit blistering).
Justification for selection of skin irritation / corrosion endpoint:
The performance of skin irritation studies is not technically feasible and scientifically unjustified.
Justification for selection of eye irritation endpoint:
The performance of eye irritation studies is not technically feasible and scientifically unjustified.
Justification for classification or non-classification
Based on the available information in the dossier, the substance 1,1,1,3,3,3-Hexafluoropropane (CAS No. 690-39-1) does not need to be classified for skin irritation/corrosion and does not need to be classified for serious eye damage/eye irritation when considering the criteria outlined in Annex I of 1272/2008/EC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
