Registration Dossier
Registration Dossier
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EC number: 267-510-5 | CAS number: 67874-81-1
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.43 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.043 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 100 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 1.29 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.129 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.257 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential to cause toxic effects if accumulated (in higher organisms) via the food chain
Additional information
Conclusion on classification
Short-term toxicity tests for fish, Daphnia and algae are available for the substance. The EC50 and LC50 values are 0.43, 0.48 and > 1.8 mg/l, respectively. For algae a NOEC of 0.51 mg/L and EC10 of 0.70 mg/L was derived. Based on the lowest LC50 for fish being below 1 mg/L classification with acute 1 (H400) needs to be applied. As one reliable long-term toxicity endpoint is available chronic classification needs to be derived on both acute and chronic data and worst case should be taken. The substance is readily biodegradable, has a log Kow of 5.1 and lowest acute data point is 0.43 mg/L for fish which would lead to classification as chronic 1 (H410). Based on chronic data Cedramber would need to be classified H412. As the worst case needs to be taken, Cedramber needs to be classified H400 (Aquatic Acute 1) and H410 (Aquatic Chronic 1) according to Regulation 1272/2008/EC (CLP). M factor for acute toxicity is 1 and for chronic no M factor is applicable.
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