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EC number: 206-376-4 | CAS number: 334-48-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- not reported
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Original report not available and documentation insufficient for assessment
- Qualifier:
- no guideline followed
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Artemia salina
- Test type:
- not specified
- Water media type:
- saltwater
- Limit test:
- no
- Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 36 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: No test duration of this short-term test is given in the publication but is assumed that the test duration might be similar to the duration of the freshwater tests.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 May - 20 May 1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- hardness of test water was lower than that recommended by the Guideline
- GLP compliance:
- yes
- Remarks:
- according to the Japanese GLP Standard
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 0 and 20 mg/L
- Sampling method: 10 mL test solution was sampled directly from each test vessel at test initiation and after 48 hours.
- Sample storage conditions before analysis: Analysis was conducted immediately after sampling, no storage. - Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: The test substance was dissolved in vehicle, and this stock solution was diluted in dilution water and stirred for 1 hour.
- Controls: dilution water with/without vehicle
- Chemical name of vehicle: dimethylformamide
- Concentration of vehicle in test medium: 0.1 mL/LGC
- Evidence of undissolved material: not observed - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flea
- Source: Bred in-house (origin: Incorporated Administrative Agency, National Institute for Environmental Studies, Tsukuba, Japan)
- Age at study initiation: max 24 hours
- Feeding during test: no
ACCLIMATION
- Acclimation period: 2 - 4 weeks
- Acclimation conditions: same as test
- Type and amount of food: Chlorella vulgaris, 0.1 - 0.2 mg C/day
- Health during acclimation: 1% mortality was observed - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Hardness:
- 55.2 mg/L (as CaCO3)
- Test temperature:
- 19.8 °C (20 ± 1 °C )
- pH:
- 7.7 - 8.1
- Dissolved oxygen:
- 7.5 - 8.5 mg/L (> 60% of saturated oxygen)
- Nominal and measured concentrations:
- nominal concentration: 20 mg/L
measured concentration: 21 mg/L (geometric mean) - Details on test conditions:
- TEST SYSTEM
- Test vessel: 100 mL beaker
- Material, fill volume: glass, 100 mL
- No. of organisms per vessel: 5
- No. of vessels per concentration: 4
- No. of vessels per control: 4
- No. of vessels per vehicle control: 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: charcoal-treated, dechlorinated and aerated tap water in Takarazuka, Japan
- Alkalinity: 55 mg/L
- Ca/Mg ratio: 16/3.3
- Culture medium different from test medium: same as test medium
- Intervals of water quality measurement: pH, oxygen content and temperature of test solutions were determined at test initiation and at the end of the study.
OTHER TEST CONDITIONS
- Photoperiod: 16 : 8 hours day-night regime
EFFECT PARAMETERS MEASURED: Mobility observed daily
TEST CONCENTRATIONS
- Justification for using less concentrations than requested by guideline: 20 mg/L was the maximum concentration to be dissolved uniformly in dilution water with vehicle (0.1 mL/L)
- Range finding study: performed
- Test concentrations: 20 mg/L
- Results used to determine the conditions for the definitive study: mobility inhibition was not observed - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate (reagent grade)
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 20 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 21 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- - Behavioural abnormalities: no abnormality was observed
- Mortality of control: 0%
- Other adverse effects control: not observed - Results with reference substance (positive control):
- - Results with reference substance valid? Yes
- EC50: 0.54 mg/L for 48 hours - Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- not reported
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Hyale plumulosa was studied under static marine water conditions for 48 h.
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: Capric acid was dissolved in artifical sea water by adding 10 g/L and mixing in an Erlenmeyer flask for 24 h with a magnetic bar at room temperature (25 ± 2 °C). Mixture was left still for a few hours and the upper layer was removed with a capillary pipette. The lower layer was used for testing. - Test organisms (species):
- other: Hyale plumulosa (Gammarus)
- Details on test organisms:
- TEST ORGANISM
- Common name: Gammarus
- Length at study initiation: 5 mm
- Food type: commercial fish food until test started
ACCLIMATION
- Acclimation period: 2 weeks - Test type:
- semi-static
- Water media type:
- saltwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Hardness:
- 51 mg CaCO3/L
- Test temperature:
- 25 ± 2°C
- pH:
- freshwater: 7.2
saltwater: 8.2 - Dissolved oxygen:
- If dissolved oxygen was < 60 % of air saturation, aeration was provided for 5 min at 24 h intervals.
- Salinity:
- 25 per mille
- Nominal and measured concentrations:
- Animals were exposed to a geometric series of concentrations of the test chemical (max. 1000 mg/L), but when LC50 values of the test chemicals were close to or higher than the saturated concentrations, animals were exposed only to the saturated solutions and the half-dilution of the saturated solutions.
- Details on test conditions:
- TEST SYSTEM
- Material, size, headspace, fill volume: 200 mL
- Renewal rate of test solution: after 24 h
- No. of organisms per vessel: 10 per test vessel
- Aeration: If oxygen saturation was < 60% of air saturation aeration for 5 min, at 24 h intervals.
OTHER TEST CONDITIONS
- Photoperiod: 12 h light/12 h dark - Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 41 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
Referenceopen allclose all
Table 1: Measured concentration of Decanoic acid during 48 hour exposure
Nominal Concentration (mg/L) |
Measured Concentrations (mg/L) |
Percent of nominal |
||
0 Hours (new)
|
48 Hours (old) |
Mean |
||
Control |
<0.2 |
<0.2 |
- |
- |
Solvent Control |
<0.2 |
<0.2 |
- |
- |
20 |
21 |
22 |
21 |
110 |
Table 2: Immobility of Daphnia magna
Nominal Concentration (mg/L) |
Cumulative Number of Immobilised Daphnia (Percent Immobility) |
|
|
24 Hours |
48 Hours |
Control |
0 (0) |
0 (0) |
Solvent Control |
0 (0) |
0 (0) |
20 |
0 (0) |
0 (0) |
Description of key information
EC50 (48 h) > 21 mg/L (meas. geom. mean) based on mobility of Daphnia magna (OECD 202)
Key value for chemical safety assessment
Additional information
One study on the fresh water organism Daphnia magna and two publications with salt water organisms are available testing the toxicity of decanoic acid to aquatic invertebrates.
The available study with Daphnia magna (Ministry of the Environment of Japan, 1999), was conducted according to OECD 202 and was used as the key study due to the higher reliability. The test organism was exposed in a static system to a single test item concentration of 20 mg/L (nominal). The test substance was dissolved in 0.1 mL/L dimethylformamide. An analytical monitoring was performed via GC-MS. The study did not show any toxicity effects on the test organisms and resulted in an EC50 (48 h) of > 21 mg/L (meas. geom. mean).
Supporting studies are available for marine organisms conducted with decanoic acid. Two saltwater studies (1989 and 1970) are available with the test organisms Hyale plumulosa (Gammarid) and Artemia salina resulting in LC50 (48 h) of 41 mg/L and 36 mg/L, respectively. However, the studies were both rated as insufficient for further assessment due to limited documentation.
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