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EC number: 211-016-4 | CAS number: 627-89-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
Data on the aquatic toxicity of Isopentyl oleate (CAS 627-89-4)
are not available.
In accordance with Annex XI, 1.5, of Regulation (EC) No 1907/2006,
read-across to the structurally related substances Isopropyl oleate (CAS
112-11-8) and Isobutyl oleate (CAS 84988-79-4) was conducted to fulfil
the standard information requirements. In accordance with Article 13 (1)
of Regulation (EC) No 1907/2006, "information on intrinsic properties of
substances may be generated by means other than tests, provided that the
conditions set out in Annex XI are met.” In particular for aquatic
toxicity, information shall be generated whenever possible by means
other than vertebrate animal tests, which includes the use of
information from structurally related substances (grouping or
read-across). According to Annex XI, Item 1.5, of Regulation (EC) No
1907/2006 substances can be considered to be similar if their
physicochemical, toxicological and ecotoxicological properties are
likely to be similar or follow a regular pattern as a result of
structural similarity.
Isopentyl oleate (CAS 627-89-4) is an UVCB substance comprising saturated and unsaturated linear C16-C18 fatty acids esterified with a branched C5 alcohol. The source substance Isobutyl oleate (CAS 84988-79-4), is a branched C4 alcohol esterified with a linear C14-C18 linear saturated and unsaturated fatty acid chains. Whereas Isopropyl oleate (CAS 112-11-8) is a branched C3 alcohol esterified with saturated and unsaturated linear C14-C18 fatty acid chains. The read across substances cover the alcohol moiety as well as the longest and shortest fatty acid chains of the target substance.
The target and the source substances are characterised by a low
water solubility, low vapour pressure and comparable log Koc values.
Thus, the substances are expected to have a similar environmental fate
and ecotoxicity profile.
In accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5, grouping and read-across the target substance Isopentyl oleate (CAS 627-89-4) is not considered to be harmful to aquatic organisms based on the results of the available read across studies conducted with fish, aquatic invertebrates and algae and long-term results on toxicity to aquatic invertebrates.
Experimental data on the acute toxicity of the read-across substance Isopropyl oleate (CAS 112-11-8) are available for fish and aquatic invertebrates. No toxicity of the substance was determined up to the limit of water solubility. Comparable results were obtained in the acute toxicity test on the read-across substance Isobutyl oleate (CAS 84988-79-4). The studies determined no adverse effects on fish, aquatic invertebrates and algae up to the limit of water solubility.
Data on chronic toxicity are available for the read-across substance Isobutyl oleate (CAS 84988-79-4). The long-term toxicity of the substance to Daphnia magna was tested. An effect on survival and reproduction rate of the daphnids was not observed up to the limit of water solubility (NOELR (21 d) ≥ 100 mg/L).
Data on the toxicity to microorganisms are available for the read-across substance Isopropyl oleate (CAS 112-11-8). Adverse effects of the substances to microorganisms were not observed.
The available acute and chronic toxicity data of the read-across substances demonstrate that toxic effects of the target substance Isopentyl oleate (CAS 627-89-4) up to the limit of water solubility are not likely. Consequently, additional acute and chronic testing is omitted. Based on the result from structurally related read-across substances (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) it can be concluded that Isopentyl oleate (CAS 627-89-4) will not show toxic effects on freshwater organisms up to the limit of the water solubility (WS < 3 µg/L at 20 °C).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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