Registration Dossier
Registration Dossier
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EC number: 813-338-6 | CAS number: 106155-02-6
Endpoint summary
Administrative data
Description of key information
Daphnia:
Three studies are available to evaluate the acute toxicity to aquatic invertebrates
1) Key Study on a similar substance: Experimental study, guideline EPA OPPTS 850.1010, performed under GLP conditions.
The test item is the substance 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol (CAS 28219-61-6; EC 248-908-8).
Result is EC50(48h) = 1.4 mg/L
2) Supporting QSAR estimation on a similar substance: Estimation done with ECOSAR v1.11 (QSAR model from the U.S. EPA)
The substance used for the calculation is 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol (CAS 28219-61-6; EC 248-908-8).
Result is EC50(48h) = 1.03 mg/L
3) Supporting QSAR estimation on the substance under registration (i.e as defined in section 1 of this dossier).
Estimation done with ECOSAR v1.11 (QSAR model from the U.S. EPA)
Result is EC50(48h) = 1.7 mg/L
Fish:
The following LC-values were determined:
LC0 = 2.6 mg/L
LC50 = 6.3 mg/L
LC100 = 8.5 mg/L
Algae:
Three studies are available to evaluate the toxicity to aquatic algae:
1) Key Study on a similar substance: Experimental study, guideline EPA OPPTS 850.5400, performed under GLP conditions.
The test item is the substance 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol (CAS 28219-61-6; EC 248-908-8).
Result is EC50(96h) = 2.5 mg/L, NOEC(96h)=0.4 mg/L
2) Supporting QSAR estimation on a similar substance: Estimation done with ECOSAR v1.11 (QSAR model from the U.S. EPA)
The substance used for the calculation is 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol (CAS 28219-61-6; EC 248-908-8).
Result is EC50(96h) = 1.9 mg/L
3) Supporting QSAR estimation on the substance under registration (i.e as defined in section 1 of this dossier).
Estimation done with ECOSAR v1.11 (QSAR model from the U.S. EPA)
Result is EC50(96h) = 2.8 mg/L
Microorganismes:
The following effect concentrations were determined:
EC0: 30 mg/L
EC10: 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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