Registration Dossier
Registration Dossier
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EC number: 603-157-9 | CAS number: 12676-29-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- April 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed according to OECD Guideline and to Good Laboratory Practice
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Boron silicate
- EC Number:
- 603-157-9
- Cas Number:
- 12676-29-8
- Molecular formula:
- H7 B7 Si57 O128
- IUPAC Name:
- Boron silicate
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Lot Number: 97731275LO
Purity: > 90%
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- ICP-MS
Test solutions
- Vehicle:
- no
- Details on test solutions:
- Test solutions at different concentrations were prepared by directly adding appropriate
amounts of the test substance to the growth medium and then facilitating its dispersion by
ultrasonication for 30 min.
Test organisms
- Test organisms (species):
- Chlorella vulgaris
- Details on test organisms:
- The freshwater microalga species, Chlorella vulgaris Be ij., were selected according to the recommendation of OECD guidelines. They are obtained
from Institute of Hydrobiology, Chinese Academy of science.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
Test conditions
- Test temperature:
- 23 - 24 °C
- pH:
- 7.25 - 7.66
- Nominal and measured concentrations:
- 150 mg/L (nominal)
2.99 mg/L (measured) - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 150 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Results with reference substance (positive control):
- EC50-72 h: 0.66 mg/L
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
