Registration Dossier
Registration Dossier
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EC number: 214-288-2 | CAS number: 1119-86-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The LC50 after 96 hours was 14.1 (10.0 - 20.0) mg/L (nominal test item concentration).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 14.1 mg/L
Additional information
The acute toxicity of the test item to zebrafish was determined according to the principles of the OECD-Guideline No. 203 and EU Method C.1. It is therefore, given the reliability rating of 1 (reliable without restrictions).
An acute toxicity test under semi-static conditions with renewal of the test media after 48 hours was conducted with the nominal test item concentrations of 1.25, 2.50, 5.00, 10.0 and 20.0 mg/L (factor 2). Duration of the test was 96 hours. Seven test organisms were exposed to each test concentration and the control. Water quality parameters (i.e. temperature, pH-value and oxygen- saturation) measured at 0, 24, 48, 72 and 96 hours were determined to be within the acceptable limits.
All validity criteria of the test guideline were met.
The test item was found to cause lethal effects to zebrafish after 96 hours at a nominal test item concentration of 20.0 mg/L. The LC0 and LC100 after 96 hours was 10.0 mg/L and 20.0 mg/L (nominal test item concentration). The LC50 after 96 hours was 14.1 (10.0 - 20.0) mg/L (nominal test item concentration).
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