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Diss Factsheets
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EC number: 445-630-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 445-630-0
- EC Name:
- -
- Molecular formula:
- Unspecified
- IUPAC Name:
- 1-(acetyloxy)but-3-en-2-yl acetate; 2-hydroxybut-3-en-1-yl acetate
- Details on test material:
- - Test substance: Vinylglykoldicatet ca. 75% ig
- batch No.: Kanister 1,2,4 und 5
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- - Test organisms: Daphnia magna Straus, originally obtained from the Institute National de Recherche Chimique Appliquee, France and cultured in the laboratories of BASF since 1978.
- Age of test organisms: 2 - 24 h
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 19.6 - 20.3
- pH:
- 7.9 - 8.1
- Dissolved oxygen:
- 6.6 - 8.8 mg/l
- Details on test conditions:
- Test conditions:
-Culture and test medium: according to the OECD test guideline 202 (M4 medium)
- Test duration: 48 h
- Test temperature: 19.6 - 20.3 °C
- Oxygen content during the test: 6.6 - 8.8 mg/l
- pH-value during the test: 7.9 - 8.1
- Exposure vessels: Glass test tubes sealed with glass plugs (nominal volume 50 ml)
- Test volume: 50 ml
- Light conditions: 16:8 hours, diffuse light (about 1 - 8 microeinstein/m*m*s) at 400 - 750 nm wave length
- Number of replicates: 4
- Individuals/replicate: 5
- Observation time: 0, 24, 48 h
- Observations: swimming ability
- Preparation of stock solution: All test concentrations were weighed in separately in M4 medium by adding 100.3, 50.4, 25.1, 12.3 and 6.4 mg test substance into 1000 ml culture medium. The concentrations were stirred for approx. 5 min at 20 +/- 2 °C.
- Test concentrations: ranging from 6.25 to 100 mg/l, using a spacing factor of 2.0. A control, containing culture medium only was tested in parallel.
- Analytical dose verification: Samples from each test concentration and the control were taken at the start and the end of the experiment. - Statistical evaluation: Probit analysis of the EC50 value. The NOEC, LOEC and the EC100 were determined directyl from the raw data. - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 31.6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- 26.8 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- 64.8 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Any other information on results incl. tables
RS-Freetext:
No. of immobile daphnids after x hours in %:
Nominal test concentration (mg/l) / 0 / 24 / 48
Control / 0 / 0 / 0
6.25 / 0 / 0 / 0
12.5 / 0 / 0 / 0
25.0 / 0 / 0 / 0
50.0 / 0 / 0 / 5
100 / 0 / 75 / 100
24 hour ECx values:
EC0: 50 mg/l
EC50: > 50 - < 100 mg/l
EC100: > 100 mg/l
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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