Registration Dossier
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EC number: 226-164-5 | CAS number: 5307-14-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
By QSAR Toolbox version 3.3 predicted model the short term toxicity (LC50) in Brachydanio rerio (new name: Danio rerio) fish was estimated to be 121.41493988 mg/l for 96 hrs in static condition for test substance 2-nitro-p-phenylenediamine with mortality effects.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 121.414 mg/L
Additional information
Weight of evidence studies summarised from two predicted model as followed:
1)QSAR Toolbox version 3.3(Sustainability Support Services (Europe) AB):
By QSAR Toolbox version 3.3 predicted model the short term toxicity (LC50) in Brachydanio rerio (new name: Danio rerio) fish was estimated to be 121.41493988 mg/l for 96 hrs in static condition for test substance 2-nitro-p-phenylenediamine with mortality effects.
2) ECOSAR Version 1.10 by Environmental Protection Agency (EPA):
Based on the QSAR prediction done using the EPI Suite ECOSAR version 1.10, the 96 hours LC50 was estimated to be2515.306 mg/L on fish for substance 2-nitro-p-phenylenediamine with mortality effects.
Thus based on this available values it can be concluded that the substance 2-nitro-p-phenylenediamine shall not be classified as hazardous for fish as per the criteria of CLP regulation.
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