Registration Dossier
Registration Dossier
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EC number: 214-353-5 | CAS number: 1122-58-3
Carcinogenicity
Administrative data
Description of key information
A structural analogue is not carcinogenic.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 18 mg/kg bw/day
- Study duration:
- chronic
- Species:
- rat
- Quality of whole database:
- adequate
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The criteria for classification and labelling for carcinogenicity according to Regulation EC No. 1272/2008 are not met.
Additional information
A bioassay for carcinogenicity on a structural analogue, 4-aminopyridine, was undertaken. The results indicate that the substance was not carcinogenic. This lends support to the conclusion that DMAP is not genotoxic nor carcinogenic.
Justification for selection of carcinogenicity via oral route endpoint:
experimental result on a structural analogue
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