Registration Dossier
Registration Dossier
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EC number: 210-063-8 | CAS number: 604-26-2
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no study available
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Effects on developmental toxicity
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Based on endocrine pharmacological studies in rats ZK 9227 (17ß-hydroxy-1¿-methylandrost-4-ene-3-one) is considered as a weak androgen. According to the German TRGS 905 [1] weak androgenic steroids have to be classified as reproductive toxicants as follows:
DSD: R62, Repr. Cat. 3 (Possible risk of impaired fertility) and R63, Repr. Cat. 3 (Possible risk of harm to the unborn child)
GHS: Repr. 2 (H361fd: Suspected of damaging fertility, suspected of damaging the unborn child)
[1] TRGS 905: Technische Regeln für Gefahrstoffe ¿ Verzeichnis krebserzeugender, erbgutverändernder oder fortpflanzungsgefährdender Stoffe. Ausschuss für Gefahrstoffe (AGS), edited July 2005, www.baua.de
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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