Registration Dossier
Registration Dossier
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EC number: 221-761-7 | CAS number: 3228-02-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Mean 96h-LC50 between experimental and predicted values:
96h-LC50 = 6.15 mg/L
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 6.15 mg/L
Additional information
A validated High Accuracy QSAR value for acute toxicity of the registered substance to fish resulted in a 96 h LC50 of 4.7 mg/L. The experimental 96-hour LC50 for the same substance was 7.6 mg/L with 95% CI: 6.6–8.7 mg/L based on the geometric means of the exposure concentrations in a non-GLP study. As the experimental data are very close to the predictions, the supporting experimental data are used to calculate a mean value of the studies. The mean 96 h LC50 to be used in risk assessment for this endpoint is 6.15 mg/L.
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