Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-860-2 | CAS number: 156-60-5
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
A technique was developed to determine partition coefficients for low-molecular-weight, volatile compounds such as the test substance. The liquid:air and tissue:air partitions were determined in 0.9% saline, in olive oil, and in blood, liver, muscle, and fat tissues from rats. Human blood:air values were also determined. The test substance, as a vapour, was mixed with the matrix then incubated for 15 minutes to allow for equilibration. Samples of the headspace were analysed by gas chromatography and the partition coefficient determined.
Values were:
Human blood:air = 6.04±0.38
Rat blood:air = 9.58±0.94
Saline:air =1.41±0.04
Olive oil:air = 178±6
Rat fat:air = 148±11
Rat liver:air = 8.96±0.61
Rat muscle:air = 3.52±0.54
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
