5-({4-chloro-6-[ethyl(phenyl)amino]-1,3,5-triazin-2-yl}amino)-4-hydroxy-3-[(1-sulfo-2-naphthyl)diazenyl]naphthalene-2,7-disulfonic acid, lithium sodium salts

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

read-across based on grouping of substances (category approach)

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 201 (Alga, Growth Inhibition Test)

Principles of method if other than guideline:

The assessment of data from different sources concentrated on data obtained by methods equivalent to OECD 201
It is noted that OECD guidance on testing coloured substances does not appear to have been followed in cases where inhibitrion was noted.

GLP compliance:

not specified

Analytical monitoring:

not specified

Vehicle:

no

Test organisms (species):

Scenedesmus sp.

Test type:

static

Water media type:

freshwater

Limit test:

no

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

> 100 mg/L

Validity criteria fulfilled:

not specified

Conclusions:

Other than impact of colour and light absorption, it is not considered inhibitory to algal growth

Executive summary:

From assessment of similar sulphonated azo substances, it is concludes that CJ306 need not be classified as hazardous to aquatic organisms on the basis of effects to aquatic plants. Although some references show an inhibition of growth rates biomass at concentrations below 100 mg/l, it is considered very likely that this is mainly due to absorption of light at wavelengths liked to photosynthesis.

 

No convincing evidence has been found that the substance causes harm to aquatic plants, other than shading from the coloured material.  

 

The read-across is valid and is backed up by review documents, including an assessment of azo dyes by the Danish EPA that conclude low environmental toxicity to aquatic organisms.

 

Key value for chemical safety assessment

EC10 or NOEC for freshwater algae:

100 mg/L

Additional information

From assessment of similar sulphonated azo substances, it is concludes that CJ306 need not be classified as hazardous to aquatic organisms on the basis of effects to aquatic plants. Although some references show an inhibition of growth rates biomass at concentrations below 100 mg/l, it is considered very likely that this is mainly due to absorption of light at wavelengths liked to photosynthesis.

 

No convincing evidence has been found that the substance causes harm to aquatic plants, other than shading from the coloured material.  

 

The read-across is valid and is backed up by review documents, including an assessment of azo dyes by the Danish EPA that conclude low environmental toxicity to aquatic organisms.