Registration Dossier
Registration Dossier
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EC number: 259-571-1 | CAS number: 55290-62-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The 3-h EC50 and EC10 values are >1000 mg/L as observed in a respiration inhibition study with activated sludge of a predominantly domestic sewage. The inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations.
Key value for chemical safety assessment
Additional information
The toxicity of the substance to microorganisms was investigated in an activated sludge respiration inhibition study according to OECD guideline No 209 and in compliance with GLP criteria (BASF, 2014).
In this study activated sludge from a municipal wastewater treatment plant was exposed to nominal test substance concentrations of 0 (control), 62.5, 125, 250, 500 and 1000 mg/L for 3 hours. Test concentrations were not analytically verified. The effects on microorganisms was determined by measuring total respiration rates and comparing these to an unexposed control. No significant inhibition of respiration rates was observed at any of the concentrations tested. Based on these findings, both the 3 -h EC50 and EC10 values were determined at >1000 mg/L.
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