Registration Dossier
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EC number: 456-350-3 | CAS number: 878665-13-5
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 01 to 15 February 2006
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- OECD Guideline Study. Purity and isomers composition specified. Restrictions for inaccuracy due to extrapolation.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 27 July 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Directive 92/69/EEC
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- UK GLP Compliance Programme (inspected on August 30, 2005 / signed on November 21, 2005)
- Type of method:
- effusion method: vapour pressure balance
- Specific details on test material used for the study:
- - Storage condition of test material: approximately 4°C in the dark under nitrogen
- Temp.:
- 25 °C
- Vapour pressure:
- < 0.01 Pa
- Remarks on result:
- other: Extrapolated Vapour Pressure was 0.0000075 Pa at 25 °C
- Transition / decomposition:
- no
- Conclusions:
- Very low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 0.01 Pa).
- Executive summary:
The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline, vapour pressure balance method.
Six runs were conducted between 120 and 130°C. Vapor pressure at 25 °C was calculated by extrapolation from the mean.
The vapour pressure of the test item has been determined to be 0.0000075 Pa at 25°C.
Reference
Mean extrapolated vapour pressure from each run = 0.0075 +/- 0.0004 mPa.
Determination coefficients (R2) for the 6 runs ranged between 0.9944 and 0.9989.
Regression equations and graphs are provided in the experimental reports.
Description of key information
Very low volatility (experimental, extrapolated).
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
A reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Despite restrictions for inaccuracy, due to distant extrapolation, it is considered as a key study. The result is retained as key data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
