Registration Dossier
Registration Dossier
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EC number: 200-831-0 | CAS number: 75-01-4
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: A review paper on physico-chemical, human toxicological and ecotoxicological properties of vinyl chloride, mentioning effect of liquid vinyl chloride on eyes.
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicology Update: Vinyl Chloride.
- Author:
- Easter, M.D. and Von Burg, R.
- Year:
- 1 994
- Bibliographic source:
- J Appl Toxicol 14:301-307.
Materials and methods
Test material
- Reference substance name:
- Chloroethylene
- EC Number:
- 200-831-0
- EC Name:
- Chloroethylene
- Cas Number:
- 75-01-4
- Molecular formula:
- C2H3Cl
- IUPAC Name:
- chloroethene
Constituent 1
Results and discussion
In vivo
- Irritant / corrosive response data:
- Liquid vinyl chloride would be expected to cause frostbite injury. When placed in eyes, liquid vinyl chloride may freeze tissue and produce a chemical burn as it evaporates, causing damage to the underlying tissue.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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