2-[(2-[2-(dimethylamino)ethoxy]ethyl)methylamino]ethanol

Vapour pressure

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1990-05-30 to 1990-05-31

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

GLP compliance:

yes (incl. QA statement)

Type of method:

isoteniscope

Specific details on test material used for the study:

- Name of test material (as cited in study report): Texacat ZF-10, 2-[[2-[2-(dimethylamino)ethoxy]ethyl]methylamino]ethanol
- Physical state: Clear colourless liquid
- Analytical purity: 97%
- Lot/batch No.: 90/329
- Expiration date of the lot/batch: Approximately two years from receipt (received on 30 March 1990)
- Storage condition of test material: Dark at room temperature

Key result

Temp.:

25 °C

Vapour pressure:

12 Pa

Remarks on result:

other: ± 4 Pa

Conclusions:

The vapour pressure of the test substance has been determined as 12 ± 4 Pa at 25°C (298K).

Reference 2

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2003-02-26 to 2003-06-05

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

GLP compliance:

no

Remarks:

Test facility was not GLP recognized.

Type of method:

isoteniscope

Specific details on test material used for the study:

- Name of test material (as cited in study report): Jeffcat ZF-10, 2-((2-(2-(dimethylamino)ethoxy)ethyl)methyl-amino)-ethanol
- Substance type: Amine
- Physical state: Clear colourless liquid
- Analytical purity: 99%
- Lot/batch No.: 324756
- Storage condition of test material: 22 °C in the dark

Temp.:

0 °C

Vapour pressure:

1.33 Pa

Temp.:

10 °C

Vapour pressure:

3.2 Pa

Key result

Temp.:

25 °C

Vapour pressure:

10 Pa

Temp.:

30 °C

Vapour pressure:

13.33 Pa

Temp.:

40 °C

Vapour pressure:

28 Pa

Temp.:

50 °C

Vapour pressure:

53.33 Pa

The isoteniscope method was employed for vapour pressure determination (American Society for Testing Materials: ASTM D2879-92, as recommended by the OECD).

Conclusions:

The vapor pressure was determined to be 10 Pa at 25°C.

Description of key information

The vapour pressure of the test substance was determined to be 12 ± 4 Pa at 25°C (298K) in a GLP-compliant study conducted according to methods described in EEC Directive 67/548, Annex V, A4. as published in 84/449/EEC and similar to the OECD guideline 104 performed by Huntingdon Research Centre Ltd. (1990).

The study was considered to be reliable without restrictions (Klimisch 1).

Key value for chemical safety assessment

Vapour pressure:

12 Pa

at the temperature of:

25 °C

Additional information

A supporting study performed according to the OECD 104, performed by BC Research Inc. (20003) and considered reliable without restrictions and reports a vapour pressure of 10 Pa at 25°C which is in line with the key value.