Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Short description of human case studies. Not melamine but effects of a melamine containing plastic material is reported.

Data source

Reference
Reference Type:
publication
Title:
Dermatoses provoquées par la mélamine
Author:
Soubrier R, Burlet P
Year:
1972
Bibliographic source:
Arch. Mat. Prof. Trav. Sec. Soc. 33, pp. 202-204

Materials and methods

Study type:
other: survey of workers
Principles of method if other than guideline:
Observation of workers for clinical signs.
GLP compliance:
no

Test material

Constituent 1
Reference substance name:
A melamine containing plastic material.
IUPAC Name:
A melamine containing plastic material.

Results and discussion

Applicant's summary and conclusion

Executive summary:

Some workers engaged in the production of melamine-formaldehyde products had dermatoses. The authors consider changes to be due to irritation. The source also mentions that there seems to be no sensitisation to melamine, at least under the conditions of utilising it in the plant.