Registration Dossier
Registration Dossier
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EC number: 455-940-8 | CAS number: -
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented company data which meets basic scientific principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes
Test material
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Chemical identifier as per section 1.1 and 1.2.
Batch: 021302
Conditions for storage: Ambient temperature.
Constituent 1
Test organisms
- Test organisms (species):
- activated sludge
Results and discussion
Any other information on results incl. tables
The test substance inhibited the respiration of the activated sludge in a concentration dependent extent. The highest obtained inhibition was 94.8%.
The pH of the incubation mixture after the 3 hours incubation was between 8.29 and 8.35. The test substance did not influence the pH. The following EC values for the test substance were obtained:
EC20: 14 mg/L ( EC-Value) 6 -22mg/L ( 95% confidence limits)
EC50: 37mg/L ( EC- value) 21 to 53 mg/L ( 95% confidence limits)
EC80: 103mg/L ( EC- value) 73 to 133 mg/L ( 95% confidence limits)
Applicant's summary and conclusion
- Conclusions:
- The test substance inhibited the respiration of the activated sludge in a concentration dependent extent. The highest obtained inhibition
was 94.8%.
The pH of the incubation mixture after the 3 hours incubation was between 8.29 and 8.35. The test substance did not influence the pH.
The following EC values for the test substance were obtained:
EC20: 14 mg/L ( EC-Value) 6 -22mg/L ( 95% confidence limits)
EC50: 37mg/L ( EC- value) 21 to 53 mg/L ( 95% confidence limits)
EC80: 103mg/L ( EC- value) 73 to 133 mg/L ( 95% confidence limits)
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