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Diss Factsheets
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EC number: 931-584-3 | CAS number: 66071-92-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
- 96 h LL50 value for Pimephales promelas > 527 mg/l (dwt) (>1000 mg/l (wwt.)) (OECD 203 study)
Key value for chemical safety assessment
Additional information
The sublethal effects of Black liquor to fish have also been studied, i.e. impacts on xenobiotic metabolism in fish liver and estrogenic effects to fish. Xenobiotic metabolism has been studied by measuring UDP-glucuronosyltransferase (UDPGT) and mixed function oxygenase (MFO) activities, particularly cytochrome P450-dependent enzyme EROD (7-ethoxyresorufin-0-deethylase). Estrogenic effects have been studied by detecting the egg yolk precursor vitellogenin (Vg) in plasma of exposed brown trout (Salmo trutta).
Liver EROD activity of rainbow trout (Oncorhynchus mykiss) has been reported to increase significantly when exposed to Black liquor concentrations 0.001-0.1% (v/v) (about 0.012-1.2 mg/l). With exposure concentrations of 0.01-0.023% of Black liquor in two separate studies the EROD activities varied in the range 0.29-12.03 pmol/mg/min, most values beeing under 5.0 pmol/mg/minRespectively the relative EROD induction (at Black liquor concentration 0.01%) has varied between 1.01-41.33 (Hodson et al., 1997 and Martel et al., 1994).
No effects of Black liquor were reported on UDPGT (Sturm & al., 1999). No vitellogen induction was detected either in the fish exposed to Black liquor (Sherry et al., 1999).
References:
- Hodson & al., Environmental Toxicology and Chemistry, Vol. 16, No. 5, pp. 908-916, 1997
- Martel & al., Wat. Res., Vol 28, No. 8, pp. 1835 -1844, 1994
- Sturm & al., Bull. Environ. Contam. Toxicol., Vol 62, No. 5, pp. 608 -615, 1999
- Sherry & al., The Science of the Total Environment Vol. 225, Issues 1 -2, pp.13 -31, 1999
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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