Registration Dossier
Registration Dossier
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EC number: 500-044-5 | CAS number: 25791-96-2 1 - 6.5 moles propoxylated
Endpoint summary
Administrative data
Description of key information
Acute toxicity via oral route LD50 was determined as >2000 mg/kg bw as per OECD guideline 401 and >2500 mg/kg bw as per OECD 423. The acute toxicity via dermal route was determined as >2000 mg/kg bw as per OECD guideline 402.
Key value for chemical safety assessment
Additional information
Acute toxicity via the oral route was low and the reported LD50 is >2000 mg/kg bw in two studies according to OECD guideline 401 and in one study according to OECD 423. No signs of overt systemic toxicity were observed at the limit dose of 2000 mg/kg bw.
The acute toxicity via the dermal route was low and the reported LD50 is >2000 mg/kg bw in a study according to OECD guideline 402.
LD50 values were > 2000 mg/kg bw for both the oral and dermal routes of exposure.
Justification for classification or non-classification
The results do not warrant classification according to EU GHS.
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